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MicroRNAs as Potential Pharmaco-targets in Ischemia-Reperfusion Injury Compounded by Diabetes.
(
MDPI
, 2019 , Article)
Ischemia-Reperfusion (I/R) injury is the tissue damage that results from re-oxygenation of ischemic tissues. There are many players that contribute to I/R injury. One of these factors is the family of microRNAs (miRNAs), ...
Abdominal Fat Is Directly Associated With Inflammation In PersonsWith Type-2 Diabetes Regardless Of Glycemic Control – A Jordanian Study
(2019 , Article)
Background and aim: Systemic inflammation is related to the progression of complications
associated with diabetes. This study aimed to investigate the association between
general and abdominal obesity and inflammation ...
Resveratrol-Elicited PKC Inhibition Counteracts NOX-Mediated Endothelial to Mesenchymal Transition in Human Retinal Endothelial Cells Exposed to High Glucose
(
MDPI
, 2021 , Article)
Diabetes-associated long-term hyperglycaemia leads to oxidative stress-mediated fibrosis in different tissues and organs. Endothelial-to-mesenchymal-transition (EndMT) appears to play a role in diabetes-associated fibrotic ...
Crosstalk Between Oxidative Stress and Endoplasmic Reticulum (ER) Stress in Endothelial Dysfunction and Aberrant Angiogenesis Associated With Diabetes: A Focus on the Protective Roles of Heme Oxygenase (HO)-1
(
Frontiers Media
, 2019 , Article Review)
Type-2 diabetes prevalence is continuing to rise worldwide due to physical inactivity and obesity epidemic. Diabetes and fluctuations of blood sugar are related to multiple micro- and macrovascular complications, that are ...
Muscle Strength and Glycaemic Control among Patients with Type 2 Diabetes.
(
MDPI
, 2020 , Article)
Poor glycaemic control is associated with chronic life-threatening complications. This cross-sectional study examined whether there is an association between handgrip strength and glycaemic control among patients with ...
Chinese Famine and the diabetes mellitus epidemic.
(
Nature Research
, 2019 , Article)
We thank Li et al. (The effect of the Chinese Famine on type 2 diabetes mellitus epidemics. Nat. Rev. Endocrinol. 15, 313–314 (2019))1 for their interest in our paper and agree that some studies on the association between ...
Epidemic T2DM, early development and epigenetics: implications of the Chinese Famine.
(
Nature Research
, 2018 , Article Review)
The gene-environment interactions resulting from famine and the subsequent increased intergenerational risk of type 2 diabetes mellitus (T2DM) have contributed to the current epidemic of T2DM in China, which poses major ...
Association of low serum magnesium with diabetes and hypertension: findings from Qatar Biobank Study.
(
Elsevier
, 2019 , Article)
We aimed to examine the association between serum magnesium and diabetes and hypertension among Qatari adults. In the cross-sectional study, we used data from 9693 Qatari participants) aged 20 years and above attending the ...
Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitness in US Adults
(
MDPI
, 2020 , Article)
A serum vitamin D [25-hydroxyvitamin D, 25(OH)D] concentration of ≥75 nmol/L is recommended for optimal health. We investigated the relationship between serum 25(OH)D and metabolic syndrome (MetS), diabetes, cardiometabolic ...
Involvement of Essential Signaling Cascades and Analysis of Gene Networks in Diabesity
(
MDPI
, 2020 , Article)
(1) Aims: Diabesity, defined as diabetes occurring in the context of obesity, is a serious health problem that is associated with an increased risk of premature heart attack, stroke, and death. To date, a key challenge has ...