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Organ-specific toxicity evaluation of stearamidopropyl dimethylamine (SAPDMA) surfactant using zebrafish embryos
(
Elsevier
, 2020 , Article)
Surfactants are widely used in the industry of detergents, household products, and cosmetics. SAPDMA is a cationic surfactant that is used mostly in cosmetics, conditioning agents and has recently gained attention as a ...
Analytic comparison between three high-throughput commercial SARS-CoV-2 antibody assays reveals minor discrepancies in a high-incidence population
(
Nature Research
, 2021 , Article)
Performance of three automated commercial serological IgG-based assays was investigated for assessing SARS-CoV-2 "ever" (past or current) infection in a population-based sample in a high exposure setting. PCR and serological ...
Resveratrol-Elicited PKC Inhibition Counteracts NOX-Mediated Endothelial to Mesenchymal Transition in Human Retinal Endothelial Cells Exposed to High Glucose
(
MDPI
, 2021 , Article)
Diabetes-associated long-term hyperglycaemia leads to oxidative stress-mediated fibrosis in different tissues and organs. Endothelial-to-mesenchymal-transition (EndMT) appears to play a role in diabetes-associated fibrotic ...
Distinct antibody repertoires against endemic human coronaviruses in children and adults.
(
American Society for Clinical Investigation
, 2021 , Article)
Four endemic human coronaviruses (HCoVs) are commonly associated with acute respiratory infection in humans. B cell responses to these "common cold" viruses remain incompletely understood. Here we report a comprehensive ...
Seroprevalence of West Nile Virus among Healthy Blood Donors from Different National Populations Residing in Qatar
(
Elsevier
, 2020 , Article)
ObjectiveTo estimate the age- and nationality-specific West Nile virus (WNV) seroprevalence in select Middle East and North Africa (MENA) populations residing in Qatar. MethodsSera were collected from male blood donors ...
Challenges in Laboratory Diagnosis of the Novel Coronavirus SARS-CoV-2
(
MDPI
, 2020 , Article)
The recent outbreak of the Coronavirus disease 2019 (COVID-19) has quickly spread worldwide since its discovery in Wuhan city, China in December 2019. A comprehensive strategy, including surveillance, diagnostics, research, ...
Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar
(
MDPI
, 2021 , Article)
Human parvovirus (B19V) is the causative agent of erythema infectiosum in children and
is linked to a wide range of clinical manifestations. Studies related to B19V prevalence in the Middle
East and North Africa (MENA) ...
Performance evaluation of five ELISA kits for detecting anti-SARS-COV-2 IgG antibodies
(
Elsevier
, 2020 , Article)
ObjectivesTo evaluate and compare the performances of five commercial ELISA assays (EDI, AnshLabs, Dia.Pro, NovaTec, and Lionex) for detecting anti-SARS-CoV-2 IgG. Methods70 negative control samples (collected before the ...
Hepatitis E Viruses : Emerging and Transboundary Animal Viruses
(
Springer
, 2020 , Book chapter)
Hepatitis E virus (HEV), member of genus Orthohepevirus in the family
Hepeviridae, is the leading cause of hepatitis E. More than 20 million cases of hepatitis
E virus (HEV) infection have been reported globally, out of ...
The Spectrum of Mutations of Homocystinuria in the MENA Region
(
MDPI
, 2020 , Article Review)
Homocystinuria is an inborn error of metabolism due to the deficiency in cystathionine beta-synthase (CBS) enzyme activity. It leads to the elevation of both homocysteine and methionine levels in the blood and urine. ...