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Nrf-2-dependent antioxidant and anti-inflammatory effects underlie the protective effect of esculeoside A against retinal damage in streptozotocin-induced diabetic rats
(
Elsevier
, 2024 , Article)
Esculeoside A (ESA) is a tomato-derived glycoside with antioxidant and anti-inflammatory properties. The protective effect of ESA against diabetic retinopathy is not well-investigated and was the core objective of this ...
Quantitative metabolomic and lipidomic profiling reveals aberrant amino acid metabolism in type 2 diabetes
(
Royal Society of Chemistry
, 2013 , Article)
Type 2 diabetes (T2DM) is a multi-factorial disease with a complex pathogenic mechanism; however a complete understanding of precise biochemical alterations accompanying the onset and progression of T2DM is lacking. Using ...
The predictive value of IL28B rs12979860, rs11881222 and rs8099917 polymorphisms and IP-10 in the therapeutic response of Egyptian genotype 4 patients
(
Elsevier
, 2013 , Article)
Interleukin-28B (IL28B) polymorphisms have previously been reported to be strongly associated with spontaneous and treatment-induced HCV viral clearance. AimTo assess the impact of four different IL28B polymorphisms and ...
Association of adiponectin gene polymorphism (+T45G) with acute coronary syndrome and circulating adiponectin levels
(
SAGE
, 2012 , Article)
We investigated the association of adiponectin gene polymorphisms (+T45G and +G276T) and adiponectin levels with acute coronary syndrome (ACS) among Arabs in Qatar. A case-control study was performed in 142 Arab patients ...
Genetic polymorphisms of ICAM 1 and IL28 as predictors of liver fibrosis severity and viral clearance in hepatitis C genotype 4
(
Elsevier
, 2013 , Article)
Background and objectivesIntercellular adhesion molecule-1 (ICAM-1) is located on chromosome 19p13.2, and this protein plays an important role in the pathogenesis of the hepatitis C virus (HCV). The rs12979860 polymorphism ...
Significant association of close homologue of L1 gene polymorphism rs2272522 with schizophrenia in Qatar
(
Wiley Online Library
, 2012 , Article)
Introduction: Previous reports have found that polymorphisms in the close homologue of L1 (CHL1) gene located on chromosome 3p26 are associated with schizophrenia among different ethnic populations. The aim of this study ...
Total and high molecular weight adiponectin in patients with coronary artery disease
(
Wolters Kluwer Health
, 2009 , Article)
BACKGROUND: Serum adiponectin inversely correlates with the extent of coronary artery disease (CAD). OBJECTIVES: To investigate the clinical significance of measuring high molecular weight (HMW) adiponectin in addition to ...
The cardiovascular implication of single nucleotide polymorphisms of chromosome 9p21 locus among Arab population
(
Wolters Kluwer Health
, 2015 , Article)
Background: Based on several reports including genome-wide association studies, genetic variability has been linked with higher (nearly half) susceptibility toward coronary artery disease (CAD). We aimed to evaluate the ...
Hypoadiponectinemia in obese and diabetic subjects in the State of Qatar
(
Karger
, 2008 , Article)
Background: Obesity is commonly associated with insulin resistance (IR), and is a common cause of type 2 diabetes. Adiponectin is an adipose tissue protein that enhances insulin sensitivity and has anti-atherogenic properties. ...
The prevalence of vitamin d deficiency among female college students at Qatar University
(
Saudi Arabian Armed Forces Hospital
, 2011 , Article)
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