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Now showing items 11-20 of 20
Expression profile of MicroRNA: An Emerging Hallmark of Cancer.
(
Bentham Science Publishers
, 2019 , Article Review)
MicroRNA (miRNAs), a class of small, endogenous non-coding RNA molecules of about 21-24 nucleotides in length, have unraveled a new modulatory network of RNAs that form an additional level of post-transcriptional gene ...
Estrogen in vascular smooth muscle cells: A friend or a foe?
(
Elsevier Inc.
, 2018 , Article Review)
Cardiovascular disease (CVD) continues to be the leading cause of death worldwide. The effect of estrogen on these diseases has been assessed in in vitro and in vivo models, as well as in observational studies. Collectively, ...
Impaired cross-talk between NO and hyperpolarization in myoendothelial feedback: a novel therapeutic target in early endothelial dysfunction of metabolic disease
(
Elsevier Ltd
, 2019 , Article Review)
Over the past three decades, our view of the endothelium rapidly evolved from a static lining of the blood vessels to a dynamic determinant and regulator of vascular tone and homeostasis. It is now widely accepted that ...
Inositol 1,4,5-Trisphosphate Receptors in Hypertension.
(
Frontiers Media
, 2018 , Article Review)
Chronic hypertension remains a major cause of global mortality and morbidity. It is a complex disease that is the clinical manifestation of multiple genetic, environmental, nutritional, hormonal, and aging-related disorders. ...
Therapeutic angiogenesis: From conventional approaches to recent nanotechnology-based interventions
(
Elsevier Ltd
, 2019 , Article Review)
Intentional and regulated induction of blood vessels formation which is generally referred to as therapeutic angiogenesis has a lot of potential in the management of various kinds of ischemic complications as well as in ...
Epstein–Barr Virus Epidemiology, Serology, and Genetic Variability of LMP-1 Oncogene Among Healthy Population: An Update
(
Frontiers Medi
, 2018 , Article Review)
The Epstein–Barr virus (EBV) is a DNA lymphotropic herpesvirus and the causative agent
of infectious mononucleosis. EBV is highly prevalent since it affects more than 90% of
individuals worldwide and has been linked to ...
Prevalence of nephropathy in type 1 diabetes in the Arab world: A systematic review and meta-analysis
(
John Wiley and Sons Ltd
, 2018 , Article Review)
The aim of this study was to conduct a systematic review and meta-analysis and determine the prevalence of diabetic nephropathy (DN) among Arab patients with T1D. A systematic literature search was conducted using 4 different ...
Meta-analysis of the incidence of lead dislodgement with conventional and leadless pacemaker systems
(
Blackwell Publishing Inc.
, 2018 , Article Review)
Introduction
Leadless cardiac pacemaker (LCP) implantation using a transcatheter was recently developed to avoid pocket- and lead-related complications. Although a LCP has an active fixation mechanism using tines or a ...
A potential link between oxidative stress and endothelial-to-mesenchymal transition in systemic sclerosis
(
Frontiers Media S.A.
, 2018 , Article Review)
Systemic sclerosis (SSc), an autoimmune disease that is associated with a number of genetic and environmental risk factors, is characterized by progressive fibrosis and microvasculature damage in the skin, lungs, heart, ...
The role of α2-adrenergic receptors in hypertensive preeclampsia: A hypothesis
(
Wiley Blackwell
, 2019 , Article Review)
Preeclampsia, a major disorder of human pregnancy, manifests as persistent hypertension and proteinuria presenting after 20 weeks of pregnancy. Multiple systemic symptoms might be associated with preeclampsia including ...