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AuthorShkoor, Mohanad
AuthorAl-Abade, Ayahtallah
AuthorAleteiwib, Ibtesam
AuthorAl-Talib, Mahmoud
AuthorTashtoush, Hasan
Available date2017-10-25T06:57:39Z
Publication Date2017-08-18
Publication NameSynthetic Communications
Identifierhttp://dx.doi.org/10.1080/00397911.2017.1332225
CitationMohanad Shkoor, Ayahtallah Al-Abade, Ibtesam Aleteiwib, Mahmoud Al-Talib & Hasan Tashtoush "Unusual product from the acid-catalyzed one-pot, multicomponent reaction of thiocarbohydrazide, aldehydes, and phenacyl bromides" Synthetic Communications (2017) Volume 47, Issue 16
ISSN00397911
URIhttp://hdl.handle.net/10576/5718
AbstractA one-pot, three-component protocol for the synthesis of novel five-membered thiazole ring bonded to two hydrazone motifs is described. The acid-catalyzed reaction of one equivalent of thiocarbohydrazide, two equivalents of aromatic aldehydes, and one equivalent of phenacyl bromides afforded the five-membered thiazole ring. The reactions proceed with novel chemoselectivity. Similar reported protocols have always afforded 1,3,4-thiadiazines.
SponsorThe financial support of this work by the Deanship of Graduate Studies and Research at Yarmouk University is highly acknowledged (project no. 29/2014).
Languageen
PublisherTaylor & Francis
SubjectChemoselectivity
hydrazones
multicomponent reaction
thiazole
thiocarbohydrazide
thiocarbohydrazone
TitleUnusual product from the acid-catalyzed one-pot, multicomponent reaction of thiocarbohydrazide, aldehydes, and phenacyl bromides
TypeArticle
Pagination1471-1477
Issue Number16
Volume Number47


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