Browsing Biomedical Research Center by Author "Zeidan, Asad"
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Advances in Cardiovascular Biomarker Discovery.
Ghantous, Crystal M; Kamareddine, Layla; Farhat, Rima; Zouein, Fouad A; Mondello, Stefania; Kobeissy, Firas; Zeidan, Asad... more authors ... less authors ( MDPI , 2020 , Article Review)Cardiovascular diseases are the leading causes of mortality worldwide. Among them, hypertension and its pathological complications pose a major risk for the development of other cardiovascular diseases, including heart ... -
Disturbed hemodynamics and oxidative stress interaction in endothelial dysfunction and AAA progression: Focus on Nrf2 pathway
Maram, Hasan; Al-Thani, Hassan; El-Menyar, Ayman; Zeidan, Asad; Al-Thani, Asmaa; Yalcin, Huseyin C.... more authors ... less authors ( Elsevier , 2023 , Article Review)Hemodynamic shear stress is one of the major factors that are involved in the pathogenesis of many cardiovascular diseases including atherosclerosis and abdominal aortic aneurysm (AAA), through its modulatory effect on the ... -
Enteric pathogens modulate metabolic homeostasis in the Drosophila melanogaster host
Hoda, Najjar; Al-Ashmar, Sarah; Qush, Abeer; Al-Asmar, Jawaher; Rashwan, Sara; Elgamal, Abdelrahman; Zeidan, Asad; Kamareddine, Layla... more authors ... less authors ( Elsevier , 2022 , Article)On quotidian basis, living beings work out an armistice with their microbial flora and a scuffle with invading pathogens to maintain a normal state of health. Although producing virulence factors and escaping the host's ... -
Protein tyrosine phosphatase 1B inhibition improves endoplasmic reticulum stress-impaired endothelial cell angiogenic response: A critical role for cell survival
ABDELSALAM, SHAHENDA S.; PASHA, MAZHAR; EL-GAMAL, HEBA; HASAN, MARAM; ELRAYESS, MOHAMED A.; ZEIDAN, ASAD; KORASHY, HESHAM M.; AGOUNI, ABDELALI... more authors ... less authors ( Spandidos publications , 2021 , Article)Endoplasmic reticulum (ER) stress contributes to endothelial dysfunction, which is the initial step in atherogenesis. Blockade of protein tyrosine phosphatase (PTP)1B, a negative regulator of insulin receptors that is ... -
Sestrin2 suppression aggravates oxidative stress and apoptosis in endothelial cells subjected to pharmacologically induced endoplasmic reticulum stress
Fatima, Munazza T; Hasan, Maram; Abdelsalam, Shahenda S; Sivaraman, Siveen K; El-Gamal, Heba; Zahid, Muhammad A; Elrayess, Mohamed A; Korashy, Hesham M; Zeidan, Asad; Parray, Aijaz S; Agouni, Abdelali... more authors ... less authors ( Elsevier , 2021 , Article)Endoplasmic reticulum (ER) stress is an inflammatory response that contributes to endothelial dysfunction, a hallmark of cardiovascular diseases, in close interplay with oxidative stress. Recently, Sestrin2 (SESN2) emerged ... -
Water-pipe smoking promotes epithelial-mesenchymal transition and invasion of human breast cancer cells via ERK1/ERK2 pathways.
Sadek, Khaled W; Haik, Mahmoud Y; Ashour, Anas A; Baloch, Tahira; Aboulkassim, Tahar; Yasmeen, Amber; Vranic, Semir; Zeidan, Asad; Al Moustafa, Ala-Eddin... more authors ... less authors ( BioMed Central Ltd. , 2018 , Article)With the increasing popularity of water-pipe smoking (WPS), it is critical to comprehend how WPS may affect women's health. The main goal of this study is to identify the potential outcome of WPS on human breast cancer ...