Browsing by Author "Zughaier, Susu M."
Now showing items 21-40 of 43
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Impact of phthalate metabolites on vitamin D levels and subclinical inflammation: national health and nutrition examination survey, 2013–2018
Mahmoud, Elhassan; Elsayed, Abdalla Moustafa; Kaleem, Muhammad Zain; Alkorbi, Hamad A.; Elshoeibi, Amgad M.; Chivese, Tawanda; Zughaier, Susu M.... more authors ... less authors ( Taylor and Francis Ltd. , 2024 , Article)This study explores the association between phthalates and total vitamin D levels and the link between phthalates exposure and subclinical inflammation using monocyte percentage to high-density lipoprotein cholesterol ratio ... -
Meningococcal Vaccines: Challenges and Prospects.
Bagwe, Priyal; Bajaj, Lotika; Gala, Rikhav; Zughaier, Susu M; Uddin, Mohammad N; D'Souza, Martin J... more authors ... less authors ( MDPI , 2020 , Article)is a gram-negative bacterium that causes a severe acute infection, called the meningococcal disease [...]. -
Metabolomics Profiling of Vitamin D Status in Relation to Dyslipidemia
Mousa, Hanaa; Elrayess, Mohamed A.; Diboun, Ilhame; Jackson, Simon K.; Zughaier, Susu M. ( MDPI , 2022 , Article)Vitamin D deficiency is a global disorder associated with several chronic illnesses including dyslipidemia and metabolic syndrome. The impact of this association with both dyslipidemia and vitamin D deficiency on metabolomics ... -
Microneedles: A new generation vaccine delivery system
Menon, Ipshita; Bagwe, Priyal; Gomes, Keegan Braz; Bajaj, Lotika; Gala, Rikhav; Uddin, Mohammad N.; D’souza, Martin J.; Zughaier, Susu M.... more authors ... less authors ( MDPI , 2021 , Article Review)Transdermal vaccination route using biodegradable microneedles is a rapidly progressing field of research and applications. The fear of painful needles is one of the primary reasons most people avoid getting vaccinated. ... -
Neisseria gonorrhoeae Ketol-Acid Reductoisomerase Is a Potential Therapeutic Target
Rigane, Emna; Zughaier, Susu M ( IntechOpen , 2022 , Book chapter)The host-adapted human pathogen Neisseria gonorrhoeae is the causative agent of sexually transmitted infection gonorrhea. The increased emergence of gonorrhea infections worldwide, associated with the surging resistance ... -
Oral Vaccine Delivery: The Coming Age of Particulate Vaccines to Elicit Mucosal Immunity
Gala, Rikhav P.; Bajaj, Lotika; Bansal, Amit; Gomes, Keegan Braz; Joshi, Devyani; Menon, Ipshita; Zaman, Rokon Uz; Zughaier, Susu M.; D’Souza, Marissa; Popescu, Carmen; D’Souza, Nigel; Knipp, Gregory T.; D’Souza, Martin J.... more authors ... less authors ( Springer , 2020 , Book chapter)With the evolution of different challenging diseases, there is an urgent need of vaccine development against them to save millions of lives around the world. Particlulate delivery system plays an important role by acting ... -
Pathogenicity and virulence of monkeypox at the human-animal-ecology interface
Islam, Md Mazharul; Dutta, Pronesh; Rashid, Rijwana; Jaffery, Syed Shariq; Islam, Ariful; Farag, Elmoubashar; Zughaier, Susu M.; Bansal, Devendra; Hassan, Mohammad Mahmudul... more authors ... less authors ( Taylor & Francis , 2023 , Article)Monkeypox (Mpox) was mostly limited to Central and Western Africa, but recently it has been reported globally. The current review presents an update on the virus, including ecology and evolution, possible drivers of ... -
PCovNet: A presymptomatic COVID-19 detection framework using deep learning model using wearables data
Abir, Farhan Fuad; Alyafei, Khalid; Chowdhury, Muhammad E.H.; Khandakar, Amith; Ahmed, Rashid; Hossain, Muhammad Maqsud; Mahmud, Sakib; Rahman, Ashiqur; Abbas, Tareq O.; Zughaier, Susu M.; Naji, Khalid Kamal... more authors ... less authors ( Elsevier , 2022 , Article)While the advanced diagnostic tools and healthcare management protocols have been struggling to contain the COVID-19 pandemic, the spread of the contagious viral pathogen before the symptom onset acted as the Achilles' ... -
Prevalence of asymptomatic hyperuricemia and its association with prediabetes, dyslipidemia and subclinical inflammation markers among young healthy adults in Qatar
Al Shanableh, Yasemin; Hussein, Yehia Y.; Saidwali, Abdul Haseeb; Al-Mohannadi, Maryam; Aljalham, Budoor; Nurulhoque, Hamnah; Robelah, Fahad; Al-mansoori, Areej; Zughaier, Susu M.... more authors ... less authors ( BMC , 2022 , Article)Aim: The aim of this study is to investigate the prevalence of asymptomatic hyperuricemia in Qatar and to examine its association with changes in markers of dyslipidemia, prediabetes and subclinical inflammation. Methods: ... -
Prognostic Model of ICU Admission Risk in Patients with COVID-19 Infection Using Machine Learning
Islam, Khandaker R.; Kumar, Jaya; Tan, Toh L.; Reaz, Mamun B.; Rahman, Tawsifur; Khandakar, Amith; Abbas, Tariq; Hossain, Md. S.; Zughaier, Susu M.; Chowdhury, Muhammad E. H.... more authors ... less authors ( MDPI , 2022 , Article)With the onset of the COVID-19 pandemic, the number of critically sick patients in intensive care units (ICUs) has increased worldwide, putting a burden on ICUs. Early prediction of ICU requirement is crucial for efficient ... -
QCovSML: A reliable COVID-19 detection system using CBC biomarkers by a stacking machine learning model
Tawsifur, Rahman; Khandakar, Amith; Abir, Farhan Fuad; Faisal, Md Ahasan Atick; Hossain, Md Shafayet; Podder, Kanchon Kanti; Abbas, Tariq O.; Alam, Mohammed Fasihul; Kashem, Saad Bin; Islam, Mohammad Tariqul; Zughaier, Susu M.; Chowdhury, Muhammad E.H.... more authors ... less authors ( Elsevier , 2022 , Article)The reverse transcription-polymerase chain reaction (RT-PCR) test is considered the current gold standard for the detection of coronavirus disease (COVID-19), although it suffers from some shortcomings, namely comparatively ... -
Real-World Effectiveness of the Varicella Vaccine among Children and Adolescents in Qatar: A Case–Control Study
Bibi, Zahra; Nawaz, Ahmed Daniyal; Al Kurbi, Maha; Fakhroo, Shahad; Ferih, Khaled; Al-Jaber, Noor; Alex, Merin; Elawad, Khalid H.; Chivese, Tawanda; Zughaier, Susu M.... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)Background: Despite the availability of a highly efficacious vaccine, varicella outbreaks are still being reported globally. In this study, we evaluated the real-world effectiveness of varicella vaccination among children ... -
The role of soluble uric acid in modulating autophagy flux and inflammasome activation during bacterial infection in macrophages
Al-Awad, Duha; Al-Emadi, Nada; Abu-Madi, Marawan; Al-Thani, Asmaa A.; Zughaier, Susu M. ( MDPI , 2020 , Article)© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Autophagy is a homeostatic process that regulates and recycles intracellular structures and is a host defense mechanism that facilitates bacterial clearance. Uric ... -
Seroprevalence of camel brucellosis in Qatar
Alhussain, Hashim; Zughaier, Susu M.; Gawish, Ahmed; Mahmoud, Mahmoud H.; Yassine, Hadi M.; Al Thani, Asmaa; Obied, Tahra El; Al-Zeyara, Abdulaziz M.; Eltai, Nahla O.... more authors ... less authors ( Springer , 2022 , Article)Brucellosis is a significant zoonotic disease and one of the most common neglected diseases worldwide. It can infect a wide range of domestic and wild animal species. Infected animals are usually culled, causing substantial ... -
Serum 25-Hydroxyvitamin D Is Inversely Associated with Monocyte Percentage to HDL Cholesterol Ratio among Young Healthy Adults in Qatar.
Mousa, Hanaa; Islam, Nazmul; Ganji, Vijay; Zughaier, Susu M ( MDPI , 2020 , Article)Low serum 25-hydroxyvitamin D [25(OH)D] is linked to an altered lipid profile. Monocytes play an important role in inflammation and lipid metabolism. Recently, monocyte percentage to HDL-cholesterol ratio (MHR) has emerged ... -
Serum 25-Hydroxyvitamin D Is Inversely Associated with Monocyte Percentage to HDL Cholesterol Ratio among Young Healthy Adults in Qatar.
Mousa, Hanaa; Islam, Nazmul; Ganji, Vijay; Zughaier, Susu M (2020)Low serum 25-hydroxyvitamin D [25(OH)D] is linked to an altered lipid profile. Monocytes play an important role in inflammation and lipid metabolism. Recently, monocyte percentage to HDL-cholesterol ratio (MHR) has emerged ... -
Staphylococcus aureus histone deacteylase-like enzyme is a potential target for adjuvant antibiotic discovery
Chowdhury, Shazeda H.; Zughaier, Susu M. ( Hamad bin Khalifa University Press (HBKU Press) , 2022 , Article)Background: The rise in antibiotic resistance requires prompt action to reduce the burden of untreatable bacterial diseases1. Staphylococcus aureus is a human commensal and opportunistic pathogen that causes a broad range ... -
TB-CXRNet: Tuberculosis and Drug-Resistant Tuberculosis Detection Technique Using Chest X-ray Images
Rahman, Tawsifur; Khandakar, Amith; Rahman, Ashiqur; Zughaier, Susu M.; Al Maslamani, Muna; Chowdhury, Moajjem Hossain; Tahir, Anas M.; Hossain, Md Sakib Abrar; Chowdhury, Muhammad E.H.... more authors ... less authors ( Springer Nature , 2024 , Article)Tuberculosis (TB) is a chronic infectious lung disease, which caused the death of about 1.5 million people in 2020 alone. Therefore, it is important to detect TB accurately at an early stage to prevent the infection and ... -
The role of antibiotic resistance mobile genetic element MCR-1 in enhancing bacterial survival in macrophages
Hashim, Amina; Elgamal, Mahmoud; Chowdhury, Shazeda H.; Hattab, Fatima A.; Al-Shibly, Rafal; Eltai, Nahla; Al-Thani, Asmaa; Zughaier, Susu M.... more authors ... less authors ( Hamad bin Khalifa University Press (HBKU Press) , 2022 , Article)Background: Antimicrobial resistance (AMR) determinants such as mobile colistin resistance (MCR-1) that encodes colistin resistance are increasingly spreading in healthcare-associated and community-acquired infections. 1 ... -
Ultrasound Intima-Media Complex (IMC) Segmentation Using Deep Learning Models
Hassen Mohammed, Hanadi; Elharrouss, Omar; Ottakath, Najmath; Al-Maadeed, Somaya; Chowdhury, Muhammad E.H.; Bouridane, Ahmed; Zughaier, Susu M.... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)Common carotid intima-media thickness (CIMT) is a common measure of atherosclerosis, often assessed through carotid ultrasound images. However, the use of deep learning methods for medical image analysis, segmentation and ...