Browsing by Author "Rizk, Nasser M."
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The Association between Serum LDL Cholesterol and Genetic Variation in Chromosomal Locus 1p13.3 among Coronary Artery Disease Patients
Rizk, Nasser M.; El-Menyar, Ayman; Egue, Huda; Wais, Idil Souleman; Baluli, Hissa Mohamed; Alali, Khalid; Farag, Fathi; Younes, Noura; Al Suwaidi, Jassim... more authors ... less authors ( Hindawi , 2015 , Article)Background. Several polymorphisms of a locus on chromosome 1p13.3 have a significant effect on low-density lipoprotein cholesterol (LDL-C), atherosclerosis, and acute coronary syndrome (ACS). Methods. We aimed to investigate ... -
Association of adiponectin gene polymorphism (+T45G) with acute coronary syndrome and circulating adiponectin levels
Rizk, Nasser M.; El-Menyar, Ayman; Marei, Isra; Sameer, Maha; Musad, Tasneem; Younis, Dima; Farag, Fathi; Basem, Nora; Al-Ali, Khalid; Suwaidi, Jassim Al... more authors ... less authors ( SAGE , 2012 , Article)We investigated the association of adiponectin gene polymorphisms (+T45G and +G276T) and adiponectin levels with acute coronary syndrome (ACS) among Arabs in Qatar. A case-control study was performed in 142 Arab patients ... -
Association of lipid profile and waist circumference as cardiovascular risk factors for overweight and obesity among school children in Qatar
Rizk, Nasser M.; Yousef, Mervat ( Dove Medical Press , 2012 , Article)Background: Childhood obesity is a national as well as worldwide problem. The aim of this study was to evaluate the association of overweight and obesity among Qatari children with lipid profile and waist circumference as ... -
Association of β-Adrenergic Receptor Gene Polymorphisms With Acute Coronary Syndrome and Cardiovascular Risk Factors in an Arab Population
El-Menyar, Ayman; Rizk, Nasser M.; Asim, Mohammad; Al-Thani, Hassan; Elgendy, Akram; Al-Suwaidi, Jassim... more authors ... less authors ( SAGE Publications Inc. , 2016 , Article)We evaluated the association between beta-adrenergic receptor genes (ADRB1 and ADRB2) polymorphism, cardiovascular risk, and acute coronary syndrome (ACS) in individuals from an Arab ethnicity. A total of 388 Qatari ... -
Associations of Vitamin D Receptor Polymorphism rs1544410 with Adiposity Phenotypes
Sharif, Elham; Swaidan, Nuha; Shurbaji, Samar; Rizk, Nasser M. ( MedCrave , 2016 , Article)Background: Vitamin D receptor (VDR) is present on adipocytes, and many studies were performed to investigate the association between polymorphisms in VDR gene with obesity. However, in the Arab Gulf populations, whereas ... -
The cardiovascular implication of single nucleotide polymorphisms of chromosome 9p21 locus among Arab population
El-Menyar, Ayman A.; Rizk, Nasser M.; Al-Qahtani, Awad; AlKindi, Fahad; Elyas, Ahmed; Farag, Fathi; Bakhsh, Fadheela Dad; Ebrahim, Samah; Ahmed, Emad; Al-khinji, Mooza; Al-Thani, Hassan; Al Suwaidi, Jassim... more authors ... less authors ( Medknow Publications , 2015 , Article)Background: Based on several reports including genome-wide association studies, genetic variability has been linked with higher (nearly half) susceptibility toward coronary artery disease (CAD). We aimed to evaluate the ... -
The cardiovascular implication of single nucleotide polymorphisms of chromosome 9p21 locus among Arab population
El-Menyar, Ayman A.; Rizk, Nasser M.; Al-Qahtani, Awad; Alkindi, Fahad; Elyas, Ahmed; Farag, Fathi; Bakhsh, Fadheela Dad; Ebrahim, Samah; Ahmed, Emad; Al-Khinji, Mooza; Al-Thani, Hassan; Al Suwaidi, Jassim... more authors ... less authors ( Wolters Kluwer Health , 2015 , Article)Background: Based on several reports including genome-wide association studies, genetic variability has been linked with higher (nearly half) susceptibility toward coronary artery disease (CAD). We aimed to evaluate the ... -
Docosahexaenoic Acid Counteracts the Hypoxic-Induced Inflammatory and Metabolic Alterations in 3T3-L1 Adipocytes
Younes, Noura B.; Mohamed, Omnia Ahmed; Rizk, Nasser M. ( MDPI , 2022 , Article)Background: Hypoxia is caused by the excessive expansion of the white adipose tissue (AT) and is associated with obesity-related conditions such as insulin resistance, inflammation, and oxidative stress. Docosahexaenoic ... -
Early Hepatic Gene Expression Profile of Lipid Metabolism of Mice on High Fat Diet after Treatment with Anti‐Obesity Drugs
Rizk, Nasser M; Saleh, Amena; Elsayegh, Dina; Algamal, Abdelrahman ( FASEB , 2020 , Conference Paper)Obesity is a multifactorial disorder of global scale. The liver plays a vital role in fat metabolism. Disorder of hepatic fat metabolism is associated with obesity and fatty liver disease. This study aimed to detect the ... -
Elevated serum leptin levels in patients with acute myocardial infarction; Correlation with coronary angiographic and echocardiographic findings
Khafaji, Hadi A.R.Hadi; Bener, Abdul Bari; Rizk, Nasser M.; Al Suwaidi, Jassim ( Springer Nature , 2012 , Article)Background: To assess the relationship between serial serum leptin levels in patients with acute myocardial infarction (AMI) who received thrombolysis and the degree of coronary atherosclerosis, coronary reperfusion, ... -
Erratum: ITRAQ-based Quantitative Protein Expression Profiling and MRM Verification of Markers in Type 2 Diabetes (Journal of Proteome Research (2012) 11 (5527-5537) DOI: 10.1021/pr300798z)
Kaur, Prabhjit; Rizk, Nasser M.; Ibrahim, Sereen; Younes, Noura; Uppal, Arushi; Dennis, Kevin; Karve, Tejaswita; Blakeslee, Kenneth; Kwagyan, John; Zirie, Mahmoud; Ressom, Habtom W.; Cheema, Amrita K.... more authors ... less authors ( American Chemical Society (ACS) , 2013 , Article)a Serum samples obtained from individual subjects were analyzed to determine the levels of glucose, Vitamin D among others (as described in methods). The value spreads within the group for each parameter are indicated as ... -
The Expression of TBC1 Domain Family, Member 4 (TBC1D4) in Skeletal Muscles of Insulin-Resistant Mice in Response to Sulforaphane
Rizk, Nasser M; ElGamal, Abdelrahman; Elsayegh, Dina; Cakir, Isin; Ghamari-Langroudi, Masoud ( Endocrine Society , 2020 , Conference Paper)The Expression of TBC1 Domain Family, member 4 (TBC1D4) in Skeletal Muscles of Insulin-Resistant Mice in Response to Sulforaphane. Background: Obesity is commonly accompanied by impaired glucose homeostasis. Decreased ... -
The Immunophenotyping Changes of Peripheral CD4+ T Lymphocytes and Inflammatory Markers of Class III Obesity Subjects After Laparoscopic Gastric Sleeve Surgery - A Follow-Up Study
Rizk, Nasser M; Fadel, Amina; AlShammari, Wasaif; Younes, Noura; Bashah, Moataz ( Dovepress , 2021 , Article)Obesity is a chronic disorder characterized by a low-grade inflammatory state and immune cell irregularities. The study aimed to follow up on the changes in the peripheral CD4+ T lymphocytes and the pro-inflammatory ... -
Integrated datasets of proteomic and metabolomic biomarkers to predict its impacts on comorbidities of type 2 diabetes mellitus
Cheema, Amrita K.; Kaur, Prabhjit; Fadel, Amina; Younes, Noura; Zirie, Mahmoud; Rizk, Nasser M.... more authors ... less authors ( Dove Medical Press , 2020 , Article)© 2020 Cheema et al. Objective: The objective of the current study is to accomplish a relative exploration of the biological roles of differentially dysregulated genes (DRGs) in type 2 diabetes mellitus (T2DM). The study ... -
iTRAQ-based quantitative protein expression profiling and MRM verification of markers in type 2 diabetes.
Uppal, , Arushi; Dennis, Kevin; Karve, ,Tejaswita; Blakeslee, , Kenneth; Kwagyan, John; Zirie, , Mahmoud; Younes, Noura; Ibrahim, Sereen; Kaur, , Prabhjit; Rizk, Nasser M; Cheema, Amrita K... more authors ... less authors ( American Chemical Society , 2012 , Article)The pathogenesis of Type 2 diabetes mellitus (T2DM) is complex owing to molecular heterogeneity in the afflicted population. Current diagnostic methods rely on blood glucose measurements, which are noninformative with ... -
Leptin And Free Leptin Receptor Is Associated With Polycystic Ovary Syndrome In Young Women
Sharif, Elham; Rizk, Nasser M. ( Hindawi Publishing Corporation , 2015 , Article)Leptin has two forms in the circulation: free and bound forms. The soluble leptin receptor (sOB-R) circulates in the blood and can bind to leptin. The aim of this study is to assess the concentrations of the leptin and ... -
Obesity is associated with the upregulation of TLR4 protein but not associated with polymorphisms of TLR4D299G TLR4T399I
Alwakeel, Mariam; Galash, Afnan O.; Saleh, Amina; Alkhanji, FadelMooza; Rizk, Nasser M. ( Hamad bin Khalifa University Press (HBKU Press) , 2018 , Conference Paper)Title: Obesity is associated with the upregulation of TLR4 protein but not associated with polymorphisms of TLR4D299G TLR4T399I.Background: Toll-like-receptor 4 (TLR4) is a pathogen-specific receptor, expressed in white ... -
The predictive value of IL28B rs12979860, rs11881222 and rs8099917 polymorphisms and IP-10 in the therapeutic response of Egyptian genotype 4 patients
Moutaz, Derbala; Rizk, Nasser M.; Al-Kaabi, Saad; John, Anil; Sharma, Manik; El-dweik, Nazeeh; Yakoob, Rafie; Pasic, Fuad; Almohanadi, Muneera; Alejji, Khalid; Abdelmola, Abdulatif; Butt, Mohamed... more authors ... less authors ( Elsevier , 2013 , Article)Interleukin-28B (IL28B) polymorphisms have previously been reported to be strongly associated with spontaneous and treatment-induced HCV viral clearance. AimTo assess the impact of four different IL28B polymorphisms and ... -
Prevalence and Predictors of Insulin Resistance in Non-Obese Healthy Young Females in Qatar
Elrayess, Mohamed A.; Rizk, Nasser M.; Fadel, Amina S.; Kerkadi, Abdelhamid ( MDPI , 2020 , Article)The state of Qatar suffers from diabetes epidemic due to obesity-associated metabolic syndrome. However, the prevalence of insulin resistance prior to obesity, which could play an important role in the high prevalence of ... -
The prevalence of vitamin d deficiency among female college students at Qatar University
Sharif, Elham A.; Rizk, Nasser M. ( Saudi Arabian Armed Forces Hospital , 2011 , Article)N/A.