تصفح حسب المؤلف "Althani, Asmaa"
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Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA)
Sartelli, Massimo; Weber, Dieter; Ruppé, Etienne; Bassetti, Matteo; Wright, Brian; Althani, Asmaa; Marei, Hany E.... more authors ... less authors ( BioMed Central , 2016 , Article)Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients. The cornerstones in the management of complicated IAIs are timely ... -
Common and Rare Genetic Variants Associated With Alzheimer's Disease
Marei, Hany E.; Althani, Asmaa; Suhonen, Jaana; El Zowalaty, Mohamed E.; Albanna, Mohammad A.; Cenciarelli, Carlo; Wang, Tengfei; Caceci, Thomas... more authors ... less authors ( WILEY PERIODICALS, INC. , 2016 , Article)Alzheimer's disease (AD) is one of the most devastating disorders. Despite the continuing increase of its incidence among aging populations, no effective cure has been developed mainly due to difficulties in early diagnosis ... -
Human olfactory bulb neural stem cells (Hu-OBNSCs) can be loaded with paclitaxel and used to inhibit glioblastoma cell growth
Marei, Hany E.; Casalbore, Patrizia; Althani, Asmaa; Coccè, Valentina; Cenciarelli, Carlo; Alessandri, Giulio; Brini, Anna T.; Parati, Eugenio; Bondiolotti, Gianpietro; Pessina, Augusto... more authors ... less authors ( MDPI , 2019 , Article)Exploitation of the potential ability of human olfactory bulb (hOB) cells to carry, release, and deliver an effective, targeted anticancer therapy within the central nervous system (CNS) milieu remains elusive. Previous ... -
Microfluidics integrated biosensors: A leading technology towards lab-on-a-chip and sensing applications
Luka, George; Ahmadi, Ali; Najjaran, Homayoun; Alocilja, Evangelyn; DeRosa, Maria; Wolthers, Kirsten; Malki, Ahmed; Aziz, Hassan; Althani, Asmaa; Hoorfar, Mina... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2015 , Article)A biosensor can be defined as a compact analytical device or unit incorporating a biological or biologically derived sensitive recognition element immobilized on a physicochemical transducer to measure one or more analytes. ... -
Over-Expression of hNGF in Adult Human Olfactory Bulb Neural Stem Cells Promotes Cell Growth and Oligodendrocytic Differentiation
Marei, Hany E.; Althani, Asmaa; Afifi, Nahla; Abd-Elmaksoud, Ahmed; Bernardini, Camilla; Michetti, Fabrizio; Barba, Marta; Pescatori, Mario; Maira, Giulio; Paldino, Emanuela; Manni, Luigi; Casalbore, Patrizia; Cenciarelli, Carlo... more authors ... less authors ( Public Library of Science ONE Staff , 2013 , Article)The adult human olfactory bulb neural stem/progenitor cells (OBNC/PC) are promising candidate for cell-based therapy for traumatic and neurodegenerative insults. Exogenous application of NGF was suggested as a promising ... -
Recent Perspective About the Amyloid Cascade Hypothesis and Stem Cell-Based Therapy in the Treatment of Alzheimer's Disease
Marei, Hany E.; Althani, Asmaa; Suhonen, Jaana; El Zowalaty, Mohamed E.; Albanna, Mohammad A.; Cenciarelli, Carlo; Wang, Tengfei; Caceci, Thomas... more authors ... less authors ( Bentham Science , 2016 , Book chapter)Alzheimer's disease (AD) is a complex neurodegenerative condition that is clinically characterized by impaired cognitive functions. The major morphologically observed lesion of AD encompasses the accumulation of extracellular ... -
Thousands of Qatari genomes inform human migration history and improve imputation of Arab haplotypes
Razali, Rozaimi Mohamad; Rodriguez-Flores, Juan; Ghorbani, Mohammadmersad; Naeem, Haroon; Aamer, Waleed; Aliyev, Elbay; Jubran, Ali; Ismail, Said I.; Al-Muftah, Wadha; Badji, Radja; Mbarek, Hamdi; Darwish, Dima; Fadl, Tasnim; Yasin, Heba; Ennaifar, Maryem; Abdellatif, Rania; Alkuwari, Fatima; Alvi, Muhammad; Al-Sarraj, Yasser; Saad, Chadi; Althani, Asmaa; Fethnou, Eleni; Qafoud, Fatima; Alkhayat, Eiman; Afifi, Nahla; Tomei, Sara; Liu, Wei; Lorenz, Stephan; Syed, Najeeb; Almabrazi, Hakeem; Vempalli, Fazulur Rehaman; Temanni, Ramzi; Saqri, Tariq Abu; Khatib, Mohammedhusen; Hamza, Mehshad; Zaid, Tariq Abu; El Khouly, Ahmed; Pathare, Tushar; Poolat, Shafeeq; Al-Ali, Rashid; Albagha, Omar; Al-Khodor, Souhaila; Alshafai, Mashael; Badii, Ramin; Chouchane, Lotfi; Estivill, Xavier; Fakhro, Khalid A.; Mokrab, Younes; Puthen, Jithesh V.; Suhre, Karsten; Tatari, Zohreh; Clark, Andrew G.... more authors ... less authors ( Nature Research , 2021 , Article)Arab populations are largely understudied, notably their genetic structure and history. Here we present an in-depth analysis of 6,218 whole genomes from Qatar, revealing extensive diversity as well as genetic ancestries ... -
Willingness to participate in genome testing: a survey of public attitudes from Qatar
Abdul-Rahim, Hanan; Ismail, Said; Hasan, Amel; Fadl, Tasnim; Khaled, Salma; Shockley, Bethany; Nasrallah, Catherine; Qutteina, Yara; Elmaghraby, Engi; Darwish, Dima; Yasin, Heba; Fakhro, Khalid; Badji, Radja; Al-Muftah, Wadha; Afifi, Nahla; Althani, Asmaa... more authors ... less authors ( Springer , 2020 , Article)Genomics has the potential to revolutionize medical approaches to disease prevention, diagnosis, and treatment, but it does not come without challenges. The success of a national population-based genome program, like the ...