Browsing by Author "Wijten, Patrick"
Now showing items 1-2 of 2
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Jinit, Masania; Wijten, Patrick; Keipert, Susanne; Ost, Mario; Klaus, Susanne; Rabbani, Naila; Thornalley, Paul J.... more authors ... less authors ( Elsevier , 2023 , Article)Mice with ectopic expression of uncoupling protein-1 (UCP1) in skeletal muscle exhibit a healthy aging phenotype with increased longevity and resistance to impaired metabolic health. This may be achieved by decreasing ... -
Vulnerabilities of the SARS-CoV-2 Virus to Proteotoxicity—Opportunity for Repurposed Chemotherapy of COVID-19 Infection
Al-Motawa, Maryam S.; Abbas, Hafsa; Wijten, Patrick; de la Fuente, Alberto; Xue, Mingzhan; Rabbani, Naila; Thornalley, Paul J.... more authors ... less authors ( Frontiers Media , 2020 , Article)The global pandemic of COVID-19 disease caused by infection with the SARS-CoV-2 coronavirus, has produced an urgent requirement and search for improved treatments while effective vaccines are developed. A strategy for ...