تصفح حسب المؤلف "Jabeen, Ayesha"
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Anti-hypertrophic effect of Na+/H+ exchanger-1 inhibition is mediated by reduced cathepsin B
Sadaf, Riaz; Abdulrahman, Nabeel; Uddin, Shahab; Jabeen, Ayesha; Gadeau, Alain P.; Fliegel, Larry; Mraiche, Fatima... more authors ... less authors ( Elsevier , 2020 , Article)Previous studies have established the role of Na+/H+ exchanger isoform-1 (NHE1) and cathepsin B (Cat B) in the development of cardiomyocyte hypertrophy (CH). Both NHE1 and Cat B are activated under acidic conditions ... -
The co-presence of high-risk human papillomaviruses and Epstein-Barr virus is linked with tumor grade and stage in Qatari women with breast cancer.
Gupta, Ishita; Jabeen, Ayesha; Al-Sarraf, Reem; Farghaly, Hanan; Vranic, Semir; Sultan, Ali A; Al Moustafa, Ala-Eddin; Al-Thawadi, Hamda... more authors ... less authors ( Taylor and Francis , 2020 , Article)High-risk human papillomaviruses (HPV) can be present and cooperate with Epstein-Barr virus (EBV) to promote the onset and/or progression of various cancers including cervical, breast, head and neck as well as colorectal. ... -
Co-presence of human papillomaviruses and Epstein-Barr virus is linked with advanced tumor stage: a tissue microarray study in head and neck cancer patients.
Al-Thawadi, Hamda; Gupta, Ishita; Jabeen, Ayesha; Skenderi, Faruk; Aboulkassim, Tahar; Yasmeen, Amber; Malki, Mohammed I; Batist, Gerald; Vranic, Semir; Al Moustafa, Ala-Eddin... more authors ... less authors ( BMC , 2020 , Article)Human papillomaviruses (HPVs) and Epstein-Barr virus (EBV), known oncoviruses, can be co-present and cooperate in the initiation and/or progression of human carcinomas, including head and neck. Based on this fact, we ... -
CO-PREVALENCE OF HUMAN PAPILLOMAVIRUS AND EPSTEIN BARR VIRUS IN HEALTHY BLOOD DONORS IN QATAR
Gupta, Ishita; Jabeen, Ayesha; Smatti, Maria K.; Al-Thawadi, Hamda A.; Nasrallah, Gheyath K.; Sultan, Ali A.; Al-Khalaf, Moussa; Vranic, Semir; Al-Moustafa, Ala-Eddin... more authors ... less authors ( Qatar University Press , 2020 , Poster)Introduction: Infections with human oncoviruses such as high-risk human papillomaviruses (HPVs) and Epstein-Barr virus (EBV) are globally prevalent in the adult population. Both viruses are strongly associated with several ... -
Comparison of co-presence of Epstein-Barr virus and high-risk human papillomaviruses in colorectal cancers in the Middle East Region
Nagi, Karim; Gupta, Ishita; Al-Thawadi, Hamda A; Jabeen, Ayesha; Malki, Mohammed I.; Vranic, Semir; Al-Moustafa, Ala-Eddin... more authors ... less authors ( Qatar University Press , 2020 , Poster)Background: Several studies have shown the presence of onco viral DNA in colorectal tumor tissues. Viral infection by onco-viruses such as Human papillomaviruses (HPVs) and Epstein-Barr virus (EBV) are well-known to be ... -
Correction to: Co-prevalence of human Papillomaviruses (HPV) and Epstein–Barr virus (EBV) in healthy blood donors from diverse nationalities in Qatar
Gupta, Ishita; Nasrallah, Gheyath K.; Sharma, Anju; Jabeen, Ayesha; Smatti, Maria K.; Al-Thawadi, Hamda A.; Sultan, Ali A.; Alkhalaf, Moussa; Vranic, Semir; Moustafa, Ala Eddin Al... more authors ... less authors ( BMC , 2020 , Other)Correction to: Cancer Cell Int (2020) 20:107 https://doi.org/10.1186/s12935-020-01190-2 -
Co‑prevalence of human Papillomaviruses (HPV) and Epstein–Barr virus (EBV) in healthy blood donors from diverse nationalities in Qatar
Gupta, Ishita; Nasrallah, Gheyath; Sharma, Anju; Jabeen, Ayesha; Smatti, Maria; Al‑Thawadi, Hamda; Sultan, Ali; Alkhalaf, Moussa; Vranic, Semir; Al Moustafa, Ala‑Eddin... more authors ... less authors ( BMC , 2020 , Article)Background: Infections by both human oncoviruses, human Papillomaviruses (HPV) and Epstein–Barr virus (EBV) are very common in the adult human population and are associated with various malignancies. While HPV is ... -
Dasatinib and PD-L1 inhibitors provoke toxicity and inhibit angiogenesis in the embryo
Maha, Al-Asmakh; Bawadi, Hiba; Hamdan, Munia; Gupta, Ishita; Kheraldine, Hadeel; Jabeen, Ayesha; Rizeq, Balsam; Al Moustafa, Ala-Eddin... more authors ... less authors ( Elsevier , 2021 , Article)Dasatinib is a targeted cancer therapy, while programmed death ligand 1 (PD-L1) inhibitors are a form of immune checkpoint therapy used to treat various types of cancers. Several studies showed the potential efficacy of ... -
Elaeagnus angustifolia Plant Extract Inhibits Epithelial-Mesenchymal Transition and Induces Apoptosis via HER2 Inactivation and JNK Pathway in HER2-Positive Breast Cancer Cells
Jabeen, Ayesha; Sharma, Anju; Gupta, Ishita; Kheraldine, Hadeel; Vranic, Semir; Al Moustafa, Ala-Eddin; Al Farsi, Halema F... more authors ... less authors ( MDPI , 2020 , Article)Elaeagnus angustifolia (EA) is a medicinal plant used for treating several human diseases in the Middle East. Meanwhile, the outcome of extract on HER2-positive breast cancer remains nascent. Thus, we herein investigated ... -
High-Risk Human Papillomaviruses (HPV) and Epstein - Barr virus (EBV) are Commonly Present in Rectal Cancer
Gupta, Ishita; Jabeen, Ayesha; Skenderi, Faruk; Malki, Mohammed; Al-Thawadi, Hamda; Al Moustafa, Ala‑Eddin; Vranic, Semir... more authors ... less authors ( Springer Nature , 2020 , Conference Paper)Background: Human papillomaviruses (HPVs) and Epstein–Barr virus (EBV) are well-established oncoviruses that can be co-present and cooperate in the initiation and/or progression of various human cancers. We recently reported ... -
High-risk human papillomaviruses and Epstein-Barr virus in breast cancer in Lebanese women and their association with tumor grade: a molecular and tissue microarray study.
Nagi, Karim; Gupta, Ishita; Jurdi, Nawaf; Jabeen, Ayesha; Yasmeen, Amber; Batist, Gerald; Vranic, Semir; Al-Moustafa, Ala-Eddin... more authors ... less authors ( BMC , 2021 , Article)High-risk human papillomaviruses (HPVs) are present and can cooperate with Epstein-Barr virus (EBV) to initiate and/or enhance the progression of several types of human carcinomas including cervical as well as head and ... -
High-Risk Human Papillomaviruses and Epstein-Barr Virus in Colorectal Cancer and Their Association with Clinicopathological Status.
Gupta, Ishita; Al Farsi, Halema; Jabeen, Ayesha; Skenderi, Faruk; Al-Thawadi, Hamda; AlAhmad, Yaman M; Al Moustafa, Ala-Eddin; Vranic, Semir... more authors ... less authors ( MDPI , 2020 , Article)Colorectal cancer (CRC) is a common malignancy with a high mortality rate worldwide. It is a complex, multifactorial disease that is strongly impacted by both hereditary and environmental factors. The role of microbes ... -
High-risk human papillomaviruses and Epstein–Barr virus in breast cancer in Lebanese women and their association with tumor grade: a molecular and tissue microarray study
Nagi, Karim; Gupta, Ishita; Jurdi, Nawaf; Jabeen, Ayesha; Yasmeen, Amber; Batist, Gerald; Vranic, Semir; Al-Moustafa, Ala Eddin... more authors ... less authors ( Springer Nature , 2021 , Article)Background: High-risk human papillomaviruses (HPVs) are present and can cooperate with Epstein–Barr virus (EBV) to initiate and/or enhance the progression of several types of human carcinomas including cervical as well as ... -
High-risk human papillomaviruses and epstein–barr virus in colorectal cancer and their association with clinicopathological status
Gupta, Ishita; Farsi, Halema Al; Jabeen, Ayesha; Skenderi, Faruk; Al-Thawadi, Hamda; Alahmad, Yaman M.; Moustafa, Ala Eddin Al; Vranic, Semir... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2020 , Article)Colorectal cancer (CRC) is a common malignancy with a high mortality rate worldwide. It is a complex, multifactorial disease that is strongly impacted by both hereditary and environmental factors. The role of microbes ... -
Naked Poly(amidoamine) Dendrimer Nanoparticles Exhibit Intrinsic Embryotoxicity During the Early Stages of Normal Development.
Kheraldine, Hadeel; Gupta, Ishita; Alhussain, Hashim; Jabeen, Ayesha; Akhtar, Saghir; Al Moustafa, Ala-Eddin; Rachid, Ousama... more authors ... less authors ( American Science Publishers ASP , 2020 , Article)To investigate the impact of poly(amidoamine) dendrimers (PAMAMs) in the embryo, we explored the outcome of different generations (G₄ and G) on the early stages of embryogenesis using the chicken embryo as a model. We also ... -
Oncoproteins of High-Risk HPV and EBV Cooperate to Enhance Cell Motility and Invasion of Human Breast Cancer Cells Erk1/Erk2 and β-Catenin Signaling Pathways.
Gupta, Ishita; Jabeen, Ayesha; Vranic, Semir; Al Moustafa, Ala-Eddin; Al-Thawadi, Hamda ( Frontiers Media , 2021 , Article)Breast cancer is a leading cause of death in women around the world. Most breast cancer-related deaths are a result of complications from the metastatic spread. Several recent studies reported that high-risk human ...