Browsing by Author "Adaikalakoteswari, Antonysunil"
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Analysis of Serum Advanced Glycation Endproducts Reveals Methylglyoxal-Derived Advanced Glycation MG-H1 Free Adduct Is a Risk Marker in Non-Diabetic and Diabetic Chronic Kidney Disease
Rabbani, Naila; Adaikalakoteswari, Antonysunil; Larkin, James R.; Panagiotopoulos, Sianna; MacIsaac, Richard J.; Yue, Dennis K.; Fulcher, Gregory R.; Roberts, Matthew A.; Thomas, Merlin; Ekinci, Elif; Thornalley, Paul J.... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Accumulation of advanced glycation endproducts (AGEs) is linked to decline in renal function, particularly in patients with diabetes. Major forms of AGEs in serum are protein-bound AGEs and AGE free adducts. In this study, ... -
High fractional excretion of glycation adducts is associated with subsequent early decline in renal function in type 1 diabetes
Perkins, B.A.; Perkins, Bruce A.; Rabbani, Naila; Weston, Andrew; Adaikalakoteswari, Antonysunil; Lee, Justin A.; Lovblom, Leif E.; Cardinez, Nancy; Thornalley, Paul J.... more authors ... less authors ( Nature Publishing Group , 2020 , Article)Increased protein glycation, oxidation and nitration is linked to the development of diabetic nephropathy. We reported levels of serum protein glycation, oxidation and nitration and related hydrolysis products, glycation, ...