Browsing by Author "Sharif, Elham"
Now showing items 1-13 of 13
-
Association between Genetic Variants of GC Gene at 4q13.3 and Vitamin D Concentrations in Adult Females
sharif, Elham; Rizk, Nasser; Thakur, Hajera; Kurdi, Tasnim; Alwakeel, Mariam ( Longdom , 2019 , Article)Background: Vitamin D binding protein, encoded by the GC gene (on 4q13.3), plays an important role in transporting vitamin D. Several Genome-Wide Association Studies (GWASs) have established a significant association ... -
Associations of Vitamin D Receptor Polymorphism rs1544410 with Adiposity Phenotypes
Sharif, Elham; Swaidan, Nuha; Shurbaji, Samar; Rizk, Nasser M. ( MedCrave , 2016 , Article)Background: Vitamin D receptor (VDR) is present on adipocytes, and many studies were performed to investigate the association between polymorphisms in VDR gene with obesity. However, in the Arab Gulf populations, whereas ... -
Associations of Vitamin D Receptor Polymorphisms with Coronary Artery Diseases
Sharif, Elham; Rizk, Nasser; Abu Aqel, Sirin; Masoud, Ofelia (2016 , Poster)Background: Previous studies have investigated the association of rs1544410, rs7975232 and rs731236 polymorphisms on vitamin D receptor gene and its impact on diseases such as cancer, diabetes and hypertension in different ... -
The Dual Role of Paramagnetic Particles for Integrated Lysis and Measurement in a Rapid Immunoassay for Intracellular Proteins
Sharif, Elham; Kiely, Janice; Wraith, Patrick; Luxton, Richard ( IEEE , 2013 , Article)Abstract—A novel, integrated lysis and immunoassay method- ology and system for intracellular protein measurement are de- scribed. The method uses paramagnetic particles both as a lysis agent and assay label resulting ... -
The frequency of polycystic ovary syndrome in young reproductive females in Qatar
Sharif, Elham; Rahman, Sumaya; Zia, Yumna; Rizk, Nasser ( Dove Medical Press , 2016 , Article)This was a prospective cross-sectional study in which 126 female students between the ages of 18 and 30 years were evaluated for the frequency of polycystic ovary syndrome (PCOS) through clinical interview, questionnaire, ... -
Leptin And Free Leptin Receptor Is Associated With Polycystic Ovary Syndrome In Young Women
Sharif, Elham; Rizk, Nasser M. ( Hindawi Publishing Corporation , 2015 , Article)Leptin has two forms in the circulation: free and bound forms. The soluble leptin receptor (sOB-R) circulates in the blood and can bind to leptin. The aim of this study is to assess the concentrations of the leptin and ... -
Neutrophil Gelatinase Associated Lipocalin: Is not an Early Marker Inductor for Diabetic Nephropathy in Qatari Population
Sharif, Elham; Alwakeel, Mariam ( BJSTR , 2019 , Article)Background: The WHO Global Report on Diabetes (2016) showed that the number of diabetic patients quadrupled between 1980 and 2016, while causing the death of 1.5 million people. While the global prevalence of diabetes ... -
New markers for the detection of polycystic ovary syndrome
Sharif, Elham; Alwakeel, Mariam ( MedCrave Group , 2019 , Article)Polycystic Ovary Syndrome (PCOS) is a highly prevalent, complex genetic disorder of the endocrine system in women. Alterations that occur in women with PCOS can be due to several predisposing factors; among these contributors ... -
Novel immunoassay technique for rapid measurement of intracellular proteins using paramagnetic particles
Sharif, Elham; Kiely, Janice; Luxton, Richard ( Elsevier B.V. , 2013 , Article)Magnetic immunoassays have been shown to have similar detection limits to conventional immunoassays, with the advantage of reduced total assay time. The aim of this study was to demonstrate that an integrated lysis and ... -
The Relationship Between Leptin and PCOS
Sharif, Elham; Faisal, Amal; Osman, Amal; Rizk, Nasser ( De Gruyter , 2014 , Conference Paper)Background: The ob gene produces a leptin hormone that works as a satiety signal to the hypothalamus. Leptin may have a role in polycystic ovary syndrome (PCOS) via its role on obesity and insulin resistance. Materials ... -
The role of polymorphisms in vitamin d-related genes in response to vitamin d supplementation
Tomei, Sara; Singh, Parul; Mathew, Rebecca; Mattei, Valentina; Garand, Mathieu; Alwakeel, Mariam; Sharif, Elham; Khodor, Souhaila Al... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2020 , Article)Background. Vitamin D deficiency represents a major healthcare problem. Vitamin D status is influenced by genetic and environmental determinants. Several observational studies have evaluated the association of single-nucleotide ... -
The potential role of vitamin D supplementation as a gut microbiota modifier in healthy individuals
Singh, Parul; Rawat, Arun; Alwakeel, Mariam; Sharif, Elham; Al Khodor, Souhaila ( Nature Research , 2020 , Article)Vitamin D deficiency affects approximately 80% of individuals in some countries and has been linked with gut dysbiosis and inflammation. While the benefits of vitamin D supplementation on the gut microbiota have been studied ... -
TLR4 Receptor D299G/T399I Haplotype Polymorphism Is Associated with Insulin Resistance in Obese Female Subjects
Sharif, Elham; Al-Wakeel, Mariam; Mohamed, Afnan; kerkadi, Abdelhamid; Rizk, Nasser M (2020 , Article)Background: Activation of Toll-like-receptor 4 (TLR4) causes chronic inflammation that can result in obesity and metabolic syndrome (MeS). Aim: This study aimed to investigate the role of TLR4 polymorphisms of TLR4D299G/T399I, ...