تصفح حسب المؤلف "Eid, Ali H."
-
2-Nucleobase-substituted 4,6-Diaminotriazine Analogs: Synthesis and Anti-cancer Activity in 5-Fluorouracil-Sensitive and Resistant Colorectal Cancer Cells.
Hamze, Khalil; Abdallah, Rola H; Younis, Nour K; Fardoun, Manal; Darwiche, Nadine; Kobeissy, Firas; Iratni, Rabah; Bouhadir, Kamal; Eid, Ali H... more authors ... less authors ( Bentham Science Publishers , 2022 , Article)Cancer continues to be the second leading cause of death worldwide with colorectal cancer (CRC) being the third most common type. Despite significant advances in cancer therapies, current treatment of CRC remains suboptimal. ... -
Adipose tissue immunomodulation: A novel therapeutic approach in cardiovascular and metabolic diseases
Alzaim, Ibrahim; Hammoud, Safaa H.; Al-Koussa, Houssam; Ghazi, Alaa; Eid, Ali H.; El-Yazbi, Ahmed F.... more authors ... less authors ( Frontiers Media , 2020 , Article)Adipose tissue is a critical regulator of systemic metabolism and bodily homeostasis as it secretes a myriad of adipokines, including inflammatory and anti-inflammatory cytokines. As the main storage pool of lipids, ... -
Adipose tissue mitochondrial dysfunction and cardiometabolic diseases: On the search for novel molecular targets
Ibrahim, AlZaim; Eid, Ali H.; Abd-Elrahman, Khaled S.; El-Yazbi, Ahmed F. ( Elsevier , 2022 , Article)Cardiometabolic diseases present an escalating global health and economic burden. Such a surge is driven by epidemic prevalence rates of metabolic disorders, such as obesity and type 2 diabetes, and their associated ... -
An updated overview of cyanidins for chemoprevention and cancer therapy
Posadino, Anna Maria; Giordo, Roberta; Ramli, Iman; Zayed, Hatem; Nasrallah, Gheyath K.; Wehbe, Zena; Eid, Ali H.; Gürer, Eda Sönmez; Kennedy, John F.; Aldahish, Afaf Ahmed; Calina, Daniela; Razis, Ahmad Faizal Abdull; Modu, Babagana; Habtemariam, Solomon; Sharifi-Rad, Javad; Pintus, Gianfranco; Cho, William C.... more authors ... less authors ( Elsevier , 2023 , Article Review)Anthocyanins are colored polyphenolic compounds that belong to the flavonoids family and are largely present in many vegetables and fruits. They have been used in traditional medicine in many cultures for a long time. The ... -
Anti-atherosclerotic plants which modulate the phenotype of vascular smooth muscle cells
Al-Shehabi, Tuqa Saleh; Iratni, Rabah; Eid, Ali H. ( Elsevier , 2016 , Article)Background: Cardiovascular disease (CVD) remains the leading cause of global death, with atherosclerosis being a major contributor to this mortality. Several mechanisms are implicated in the pathogenesis of this disease. ... -
Anti-atherosclerotic plants which modulate the phenotype of vascular smooth muscle cells
Saleh Al-Shehabi, Tuqa; Iratni, Rabah; Eid, Ali H. ( Elsevier , 2016 , Article)Background: Cardiovascular disease (CVD) remains the leading cause of global death, with atherosclerosis being a major contributor to this mortality. Several mechanisms are implicated in the pathogenesis of this disease. ... -
Anti-hypertensive Herbs and their Mechanisms of Action: Part I
Al Disi, Sara S.; Anwar, M. Akhtar; Eid, Ali H. ( Frontiers Media , 2016 , Article)The use of herbal therapies for treatment and management of cardiovascular diseases (CVDs) is increasing. Plants contain a bounty of phytochemicals that have proven to be protective by reducing the risk of various ailments ... -
Anti-Hypertensive Herbs and Their Mechanisms of Action: Part II
Anwar, M. Akhtar; Al Disi, Sara S.; Eid, Ali H. ( Frontiers Media , 2016 , Article)Traditional medicine has a history extending back to thousands of years, and during the intervening time, man has identified the healing properties of a very broad range of plants. Globally, the use of herbal therapies to ... -
Anti-Neoplastic Effects of Annonacin against Renal Cell Carcinoma
Munusamy, Shankar; Gopalakrishnan, Akila; Ravindran, Sreenithya; Alali, Feras; Eid, Ali H. ( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)Background and Objectives: Renal cell carcinoma is the most common and lethal form of all renal cancers, and accounts for 4.1% of all cancer cases in Qatar. Mutations to Von-Hippel Lindeau (VHL) gene in renal cells activates ... -
Antibody-dependent enhancement (ADE) of SARS-CoV-2 in patients exposed to MERS-CoV and SARS-CoV-2 antigens
Thomas, Swapna; Smatti, Maria K.; Alsulaiti, Haya; Zedan, Hadeel T.; Eid, Ali H.; Hssain, Ali A.; Abu Raddad, Laith J.; Gentilcore, Giusy; Ouhtit, Allal; Althani, Asmaa A.; Nasrallah, Gheyath K.; Grivel, Jean Charles; Yassine, Hadi M.... more authors ... less authors ( Wiley , 2024 , Article)This study evaluated the potential for antibody-dependent enhancement (ADE) in serum samples from patients exposed to Middle East respiratory syndrome coronavirus (MERS-CoV). Furthermore, we evaluated the effect of severe ... -
Antihypertensive indigenous lebanese plants: Ethnopharmacology and a clinical trial
Samaha, Ali A.; Fawaz, Mirna; Salami, Ali; Baydoun, Safaa; Eid, Ali H. ( MDPI AG , 2019 , Article)Hypertension is highly prevalent among the Lebanese adult population and is indeed the major cause of mortality in Lebanon. Traditional use of antihypertensive medicinal plants has long been practiced. The aim of this study ... -
Associations of lifestyle and dietary habits with hyperlipidemia in Lebanon
Samaha, Ali A.; Zouein, Fouad; Gebbawi, Maya; Fawaz, Mirna; Houjayri, Raheel; Samaha, Rana; Baydoun, Safaa; Eid, Ali H.... more authors ... less authors ( OAE Publishing Inc. , 2017 , Article)Aim: This study was designed to evaluate the effects of dietary and lifestyle habits on several blood lipid parameters in the Lebanese population. Methods: This was a cross-sectional study for 2,000 individuals, of whom ... -
Bariatric Surgery Improves Serum CD40L Levels as a Predictor of Cardiovascular Risk: Systematic Review and Meta-analysis
Jamialahamdi, Tannaz; Eid, Ali H.; Nguyen, Ninh T.; Gadde, Kishore M.; Sukhorukov, Vasily N.; Almahmeed, Wael; Kroh, Matthew; Sahebkar, Amirhossein... more authors ... less authors (2024 , Article)CD40 and its ligand have been recently implicated in the pathogenesis of cardiovascular disease (CVD). This meta-analysis examined the effect of bariatric surgery in reducing circulating CD40L levels. A systematic review ... -
Beta-caryophyllene exhibits anti-proliferative effects through apoptosis induction and cell cycle modulation in multiple myeloma cells
Mannino, Federica; Pallio, Giovanni; Corsaro, Roberta; Minutoli, Letteria; Altavilla, Domenica; Vermiglio, Giovanna; Allegra, Alessandro; Eid, Ali H.; Bitto, Alessandra; Squadrito, Francesco; Irrera, Natasha... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2021 , Article)Cannabinoid receptors, which are widely distributed in the body, have been considered as possible pharmacological targets for the management of several tumors. Cannabinoid type 2 receptors (CB2Rs) belong to the G protein-coupled ... -
Biochemical and cellular basis of oxidative stress: Implications for disease onset
Aramouni, Karl; Assaf, Roland; Shaito, Abdullah; Fardoun, Manal; Al-Asmakh, Maha; Sahebkar, Amirhossein; Eid, Ali H.... more authors ... less authors ( Wiley , 2023 , Article Review)Cellular oxidation–reduction (redox) systems, which encompass pro- and antioxidant molecules, are integral components of a plethora of essential cellular processes. Any dysregulation of these systems can cause molecular ... -
Bridging conventional medicine and traditional, complementary, and alternative approaches: Fostering collaborative attempts for a holistic healthcare system
Eid, Ali H.; Sahebkar, Amirhossein ( Elsevier , 2023 , Other)Dear Editor, We read the paper entitled “The future of integrative health: vision, values, and principles for positive, sustainable systemic change” by Kemper, which was published last month.1 The points discussed therein ... -
Burden and disease pathogenesis of influenza and other respiratory viruses in diabetic patients
Swapna, Thomas; Ouhtit, Allal; Al Khatib, Hebah A.; Eid, Ali H.; Mathew, Shilu; Nasrallah, Gheyath K.; Emara, Mohamed M.; Al Maslamani, Muna A.; Yassine, Hadi M.... more authors ... less authors ( Elsevier , 2022 , Article Review)Over the past two decades, diabetes mellitus (DM) has been receiving increasing attention among autoimmune diseases. The prevalence of type 1 and type 2 diabetes has increased rapidly and has become one of the leading ... -
C-peptide in diabetes: A player in a dual hormone disorder?
Dakroub, Ali; Dbouk, Ali; Asfour, Aref; Nasser, Suzanne A.; El-Yazbi, Ahmed F.; Sahebkar, Amirhossein; Eid, Assaad A.; Iratni, Rabah; Eid, Ali H.... more authors ... less authors ( Wiley-Blackwell , 2024 , Article)C-peptide, a byproduct of insulin synthesis believed to be biologically inert, is emerging as a multifunctional molecule. C-peptide serves an anti-inflammatory and anti-atherogenic role in type 1 diabetes mellitus (T1DM) ... -
Cadmium induces migration of colon cancer cells: Roles of reactive oxygen species, p38 and cyclooxygenase-2
Naji, Sara; Issa, Khodr; Eid, Assaad; Iratni, Rabah; Eid, Ali H. ( Cell Physiol Biochem Press GmbH & Co KG , 2019 , Article)Background/Aims: Cadmium (Cd) is a heavy metal contaminant whose toxicity is associated with colorectal cancer (CRC). However, the underlying molecular mechanisms of Cd-induced CRC malignancy remain obscure. Methods: A ... -
CAMP induces adhesion of microvascular smooth muscle cells to fibronectin via an epac-mediated but PKA-independent mechanism
Eid, Ali H. ( Cell Physiol Biochem Press , 2012 , Article)Background/Aims: Vascular smooth muscle cells (VSMCs) play important roles, both in physiologic and pathophysiologic processes. Adhesion of these cells is critical for their proper functioning, especially in resistance-sized ...