Browsing by Author "Krishnankutty, Roopesh"
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Aryl Hydrocarbon Receptor Promotes Cell Growth, Stemness Like Characteristics, and Metastasis in Human Ovarian Cancer via Activation of PI3K/Akt, β-Catenin, and Epithelial to Mesenchymal Transition Pathways
Therachiyil, Lubna; Krishnankutty, Roopesh; Ahmad, Fareed; Mateo, Jericha M.; Uddin, Shahab; Korashy, Hesham M.... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Ovarian cancer (OC) ranks first in cancer-related deaths out of all female reproductive malignancies with high-pitched tumor relapse and chemoresistance. Several reports correlate cancer occurrences with exposure to ... -
Claudin-1, A Double-Edged Sword in Cancer.
Bhat, Ajaz A; Syed, Najeeb; Therachiyil, Lubna; Nisar, Sabah; Hashem, Sheema; Macha, Muzafar A; Yadav, Santosh K; Krishnankutty, Roopesh; Muralitharan, Shanmugakonar; Al-Naemi, Hamda; Bagga, Puneet; Reddy, Ravinder; Dhawan, Punita; Akobeng, Anthony; Uddin, Shahab; Frenneaux, Michael P; El-Rifai, Wael; Haris, Mohammad... more authors ... less authors ( MDPI , 2020 , Article Review)Claudins, a group of membrane proteins involved in the formation of tight junctions, are mainly found in endothelial or epithelial cells. These proteins have attracted much attention in recent years and have been implicated ... -
Novel Post-translational Modifications in Human Serum Albumin
Kannan, Surya; Krishnankutty, Roopesh; Souchelnytskyi, Serhiy ( Bentham , 2022 , Article)Aim: This study aims to identify novel post-translational modifications in human serum albumin by mass spectrometry. Background: Serum albumin is the most abundant protein in plasma, has many physiological functions, and ... -
Vascular endothelial growth factor (VEGF) signaling in tumour vascularization: Potential and challenges
Siveen, Kodappully Sivaraman; Prabhu, Kirti; Krishnankutty, Roopesh; Kuttikrishnan, Shilpa; Tsakou, Magdalini; Alali, Feras Q.; Dermime, Said; Mohammad, Ramzi M.; Uddin, Shahab... more authors ... less authors ( Bentham , 2017 , Article)Angiogenesis is defined as the physiological process by which new blood vessels develop from pre-existing vessels; either by sprouting or intussusception. Inhibition of angiogenesis is one of the most encouraging strategies ...