Browsing by Author "Mohsen, Mona"
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Increased Receptor Affinity and Reduced Recognition by Specific Antibodies Contribute to Immune Escape of SARS-CoV-2 Variant Omicron
Vogt, Anne-Cathrine; Augusto, Gilles; Martina, Byron; Chang, Xinyue; Nasrallah, Gheyath; Speiser, Daniel; Vogel, Monique; Bachmann, Martin; Mohsen, Mona... more authors ... less authors ( MDPI , 2022 , Article)In this report, we mechanistically reveal how the Variant of Concern (VOC) SARS-CoV-2 Omicron (B.1.1.529) escapes neutralizing antibody responses, by physio-chemical characterization of this variant in comparison to the ... -
New 3-Cyano-2-Substituted Pyridines Induce Apoptosis in MCF 7 Breast Cancer Cells
Malki, Ahmed; Mohsen, Mona; Aziz, Hassan; Rizk, Ola; Shaban, Omima; El-Sayed, Mohamed; Sherif, Zaki A.; Ashour, Hayam... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2016 , Article)The synthesis of new 3-cyano-2-substituted pyridines bearing various pharmacophores and functionalities at position 2 is described. The synthesized compounds were evaluated for their in vitro anti-cancer activities on five ...