Browsing by Author "Cyprian, Farhan"
Now showing items 1-13 of 13
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Critical appraisal of predatory journals in pathology.
AlAhmad, Yaman M; Abdelhafez, Ibrahim; Cyprian, Farhan S; Akhtar, Saghir; Skenderi, Faruk; Vranic, Semir... more authors ... less authors ( BMJ , 2019 , Article)Predatory journals refer to journals that recruit articles through aggressive marketing and spam emails, promising a quick, but not robust, review and fast open-access (OA) publication, thus compromising scholarly publishing ... -
Epstein-Barr Virus and Human Papillomaviruses Interactions and Their Roles in the Initiation of Epithelial-Mesenchymal Transition and Cancer Progression.
Cyprian, Farhan S; Al-Farsi, Halema F; Vranic, Semir; Akhtar, Saghir; Al Moustafa, Ala-Eddin ( Frontiers Media , 2018 , Article Review)Oncoviruses are implicated in around 20% of all human cancers including both solid and non-solid malignancies. Epstein-Barr virus (EBV) and human papillomaviruses (HPVs) are the most common oncoviruses worldwide. Currently, ... -
HER-2/Epstein-Barr virus crosstalk in human gastric carcinogenesis: A novel concept of oncogene/oncovirus interaction.
Cyprian, Farhan S; Al-Antary, Noor; Al Moustafa, Ala-Eddin ( Taylor & Francis , 2018 , Article)Gastric cancer is the fourth most common cancer and the second leading cause of cancer deaths worldwide. Additionally, it is well-known that metastatic cancer disease is a major cause of morbidity and mortality in cancer ... -
Immunomodulatory Effects of Vitamin D in Pregnancy and Beyond.
Cyprian, Farhan; Lefkou, Eleftheria; Varoudi, Katerina; Girardi, Guillermina ( Frontiers Media , 2019 , Article)In addition to its role in calcium homeostasis and bone formation, a modulatory role of the active form of vitamin D on cells of the immune system, particularly T lymphocytes, has been described. The effects of vitamin D ... -
An integrated multi-omic approach demonstrates distinct molecular signatures between human obesity with and without metabolic complications: a case–control study
Mir, Fayaz Ahmad; Mall, Raghvendra; Ullah, Ehsan; Iskandarani, Ahmad; Cyprian, Farhan; Samra, Tareq A.; Alkasem, Meis; Abdalhakam, Ibrahem; Farooq, Faisal; Taheri, Shahrad; Abou-Samra, Abdul Badi... more authors ... less authors ( Springer Nature , 2023 , Article)Objectives: To examine the hypothesis that obesity complicated by the metabolic syndrome, compared to uncomplicated obesity, has distinct molecular signatures and metabolic pathways. Methods: We analyzed a cohort of 39 ... -
Metabolic reprogramming of T regulatory cells in the hypoxic tumor microenvironment.
Sasidharan Nair, Varun; Saleh, Reem; Toor, Salman M; Cyprian, Farhan S; Elkord, Eyad ( Springer , 2021 , Article)Metabolic dysregulation in the hypoxic tumor microenvironment (TME) is considered as a hallmark of solid tumors, leading to changes in biosynthetic pathways favoring onset, survival and proliferation of malignant cells. ... -
Metabolic Signatures of Type 2 Diabetes Mellitus and Hypertension in COVID-19 Patients With Different Disease Severity.
Elrayess, Mohamed A; Cyprian, Farhan S; Abdallah, Abdallah M; Emara, Mohamed M; Diboun, Ilhame; Anwardeen, Najeha; Schuchardt, Sven; Yassine, Hadi M... more authors ... less authors ( Frontiers Media , 2022 , Article)Increased COVID-19 disease severity is higher among patients with type 2 diabetes mellitus and hypertension. However, the metabolic pathways underlying this association are not fully characterized. This study aims to ... -
The prevalence of adaptive immunity to COVID-19 and reinfection after recovery - a comprehensive systematic review and meta-analysis.
Chivese, Tawanda; Matizanadzo, Joshua T; Musa, Omran A H; Hindy, George; Furuya-Kanamori, Luis; Islam, Nazmul; Al-Shebly, Rafal; Shalaby, Rana; Habibullah, Mohammad; Al-Marwani, Talal A; Hourani, Rizeq F; Nawaz, Ahmed D; Haider, Mohammad Z; Emara, Mohamed M; Cyprian, Farhan; Doi, Suhail A R... more authors ... less authors ( Taylor & Francis , 2022 , Article)This study aims to estimate the prevalence and longevity of detectable SARS-CoV-2 antibodies and T and B memory cells after recovery. In addition, the prevalence of COVID-19 reinfection and the preventive efficacy of ... -
Snornas and mirnas networks underlying covid-19 disease severity
Parray, Aijaz; Mir, Fayaz A.; Doudin, Asmma; Iskandarani, Ahmad; Danjuma, Ibn M.; Kuni, Rahim A.; Abdelmajid, Alaaedin; Abdelhafez, Ibrahim; Arif, Rida; Mulhim, Mohammad; Abukhattab, Mohammad; Dar, Shoukat R.; Moustafa, Ala-Eddin A.; Elkord, Eyad; Al Khal, Abdul L.; Elzouki, Abdel-Naser; Cyprian, Farhan... more authors ... less authors ( MDPI , 2021 , Article)There is a lack of predictive markers for early and rapid identification of disease progression in COVID-19 patients. Our study aims at identifying microRNAs (miRNAs)/small nucleolar RNAs (snoRNAs) as potential biomarkers ... -
Targeted immunotherapy with a checkpoint inhibitor in combination with chemotherapy: A new clinical paradigm in the treatment of triple-negative breast cancer.
Cyprian, Farhan S; Akhtar, Saghir; Gatalica, Zoran; Vranic, Semir ( Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina , 2019 , Article Review)The treatment of several solid and hematologic malignancies with immune checkpoint inhibitors (against PD-1/PD-L1) has dramatically changed the cancer treatment paradigm. However, no checkpoint inhibitors were previously ... -
The Combination of Dasatinib and PD L1 inhibitor prevents the progression of epithelial mesenchymal transition and dramatically blocks cell invasion of HER2 positive breast cancer cells
Kheraldine, Hadeel; Gupta, Ishita; Cyprian, Farhan; Vranic, Semir; Al Moustafa, Ala-Eddin ( Qatar University Press , 2021 , Poster)Introduction: Both Dasatinib (DA), a tyrosine kinase inhibitor that is used for targeted cancer therapy, and programmed death-ligand 1 (PD-1/PD-L1) inhibitor that is an immune checkpoint therapy, play a vital role in the ... -
The prevalence of adaptive immunity to COVID-19 and reinfection after recovery - a comprehensive systematic review and meta-analysis of 12 011 447 individuals
Alshibly, Rafal; Shalaby, Rana; Musa, Omran A. H.; Hindy, George; Islam, Nazmul; Habibullah, Mohammed; Al-Marwani, Talal; Hourani, Rizeq F.; Nawaz, Ahmed D.; Haider, Mohammad Z.; Emara, Mohamed M.; Cyprian, Farhan; Doi, Suhail A. R.; Chivese, Tawanda; Matizanadzo, Joshua T.; Furuya-Kanamori, Luis (3)... more authors ... less authors ( Qatar University Press , 2021 , Poster)Research purpose: The research aims to estimate the prevalence of detectable SARS-CoV-2 antibodies, T and B memory cells after recovery, to determine the prevalence of SARS-CoV-2 reinfection, and to investigate the protective ... -
Viruses and Autoimmunity: A Review on the Potential Interaction and Molecular Mechanisms.
Smatti, Maria K; Cyprian, Farhan S; Nasrallah, Gheyath K; Al Thani, Asmaa A; Almishal, Ruba O; Yassine, Hadi M... more authors ... less authors ( MDPI , 2019 , Article)For a long time, viruses have been shown to modify the clinical picture of several autoimmune diseases, including type 1 diabetes (T1D), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), Sjögren's syndrome ...