Browsing by Author "Patrono, Carlo"
Now showing items 1-2 of 2
-
Platelet thromboxane inhibition by low-dose aspirin in polycythemia vera: Ex vivo and in vivo measurements and in silico simulation
Petrucci, Giovanna; Giaretta, Alberto; Ranalli, Paola; Cavalca, Viviana; Dragani, Alfredo; Porro, Benedetta; Hatem, Duaa; Habib, Aida; Tremoli, Elena; Patrono, Carlo; Rocca, Bianca... more authors ... less authors ( Wiley , 2022 , Article)Low-dose aspirin is currently recommended for patients with polycythemia vera (PV), a myeloproliferative neoplasm with increased risk of arterial and venous thromboses. Based on aspirin pharmacodynamics in essential ... -
Thromboxane biosynthesis and future events in diabetes: the ASCEND trial
Petrucci, Giovanna; Buck, Georgina A.; Rocca, Bianca; Parish, Sarah; Baigent, Colin; Hatem, Duaa; Mafham, Marion; Habib, Aida; Bowman, Louise; Armitage, Jane; Patrono, Carlo... more authors ... less authors ( Oxford University Press , 2024 , Article)Background and Thromboxane (TX) A2, released by activated platelets, plays an important role in atherothrombosis. Urinary 11-dehydro-Aims TXB2 (U-TXM), a stable metabolite reflecting the whole-body TXA2 biosynthesis, is ...