Browsing by Author "Ouhtit A."
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Bone benefits of fish oil supplementation depend on its EPA and DHA content
Abou-Saleh H.; Ouhtit A.; Halade G.V.; Rahman M.M. ( MDPI AG , 2019 , Article)The preventive effect of high-dose (9%) regular-fish oil (FO) against bone loss during aging has been demonstrated, but the effects of a low-dose (1%–4%) of a highly purified concentrated FO (CFO) has not been elucidated. ... -
BRIP1 overexpression is correlated with clinical features and survival outcome of luminal breast cancer subtypes
Gupta I.; Ouhtit A.; Al-Ajmi A.; Rizvi S.G.A.; Al-Riyami H.; Al-Riyami M.; Tamimi Y.... more authors ... less authors ( BioScientifica Ltd. , 2018 , Article)In Oman, breast cancer is most common, representing approximately more than 25% of all cancers in women. Relatively younger populations of patients (25-40 years) present surprisingly with an aggressive phenotype and advanced ... -
Deregulation of cell growth and apoptosis in UV-induced melanomagenesis
Ouhtit A.; Gupta I.; Gaur R.L.; Fernando A.; Abd El-Azim A.O.; Eid A.; Becker T.M.... more authors ... less authors ( Frontiers in Bioscience , 2020 , Article Review)We have previously characterized the role of p16/Rb in coordinating the early events in UVB-irradiated skin. As an extension to this work, normal melanocytes and mutant p16-inducible melanoma cell models were employed to ... -
Nanoparticle-mediated targeted drug delivery for breast cancer treatment
Liyanage P.Y.; Hettiarachchi S.D.; Zhou Y.; Ouhtit A.; Seven E.S.; Oztan C.Y.; Celik E.; Leblanc R.M.... more authors ... less authors ( Elsevier B.V. , 2019 , Article Review)Breast cancer (BC) is the most common malignancy in women worldwide, and one of the deadliest after lung cancer. Currently, standard methods for cancer therapy including BC are surgery followed by chemotherapy or radiotherapy. ... -
Unmasking the interplay between mTOR and Nox4: novel insights into the mechanism connecting diabetes and cancer
Mroueh F.M.; Noureldein M.; Zeidan Y.H.; Boutary S.; Irani S.A.M.; Eid S.; Haddad M.; Barakat R.; Harb F.; Costantine J.; Kanj R.; Sauleau E.-A.; Ouhtit A.; Azar S.T.; Eid A.H.; Eid A.A.... more authors ... less authors ( NLM (Medline) , 2019 , Article)Cancer was recently annexed to diabetic complications. Furthermore, recent studies suggest that cancer can increase the risk of diabetes. Consequently, diabetes and cancer share many risk factors, but the cellular and ...