تصفح حسب المؤلف "Althani, Asmaa A."
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Antibody-dependent enhancement (ADE) of SARS-CoV-2 in patients exposed to MERS-CoV and SARS-CoV-2 antigens
Thomas, Swapna; Smatti, Maria K.; Alsulaiti, Haya; Zedan, Hadeel T.; Eid, Ali H.; Hssain, Ali A.; Abu Raddad, Laith J.; Gentilcore, Giusy; Ouhtit, Allal; Althani, Asmaa A.; Nasrallah, Gheyath K.; Grivel, Jean Charles; Yassine, Hadi M.... more authors ... less authors ( Wiley , 2024 , Article)This study evaluated the potential for antibody-dependent enhancement (ADE) in serum samples from patients exposed to Middle East respiratory syndrome coronavirus (MERS-CoV). Furthermore, we evaluated the effect of severe ... -
Antioxidative Stress Metabolic Pathways in Moderately Active Individuals
Almuraikhy, Shamma; Anwardeen, Najeha; Doudin, Asmma; Sellami, Maha; Domling, Alexander; Agouni, Abdelali; Althani, Asmaa A.; Elrayess, Mohamed A.... more authors ... less authors ( MDPI , 2023 , Article)Physical activity (PA) is known to have beneficial effects on health, primarily through its antioxidative stress properties. However, the specific metabolic pathways that underlie these effects are not fully understood. ... -
Assessment of Broadly Reactive Responses in Patients With MERS-CoV Infection and SARS-CoV-2 Vaccination
Zedan, Hadeel T.; Smatti, Maria K.; Thomas, Swapna; Nasrallah, Gheyath K.; Afifi, Nahla M.; Hssain, Ali Ait; Abu Raddad, Laith J.; Coyle, Peter V.; Grivel, Jean Charles; Almaslamani, Muna A.; Althani, Asmaa A.; Yassine, Hadi M.... more authors ... less authors ( American Medical Association , 2023 , Article)Importance: In the ongoing COVID-19 pandemic, there remain unanswered questions regarding the nature and importance of the humoral immune response against other coronaviruses. Although coinfection of the Middle East ... -
Identification of potential natural inhibitors of the receptor-binding domain of the SARS-CoV-2 spike protein using a computational docking approach
Mathew, Shilu Mathew; Benslimane, Fatiha; Althani, Asmaa A.; Yassine, Hadi M. ( HBKU Press , 2021 , Article)Background: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the only zoonotic-origin CoV to reach the pandemic stage, to which neither an effective vaccine nor a specific therapy is available. The ... -
Impact of Moderate Physical Activity on Inflammatory Markers and Telomere Length in Sedentary and Moderately Active Individuals with Varied Insulin Sensitivity
Almuraikhy, Shamma; Sellami, Maha; Al-Amri, Hadaia Saleh; Domling, Alexander; Althani, Asmaa A.; Elrayess, Mohamed A.... more authors ... less authors ( Dove Medical Press , 2023 , Article)Introduction: Physical activity-associated immune response plays a crucial role in the aging process. This study aimed to determine the impact of short-term moderate physical activity on cytokine levels, oxidative stress ... -
Influenza prevalence and vaccine efficacy among diabetic patients in Qatar
Swapna, Thomas; Emara, Mohamed M.; Ouhtit, Allal; Nader, Joanne D.; Nasrallah, Gheyath K.; Coyle, Peter V.; Althani, Asmaa A.; Al Maslamani, Muna A.; Yassine, Hadi M.... more authors ... less authors ( Elsevier , 2023 , Article)Seasonal influenza viruses may lead to severe illness and mortality in patients with comorbidities, including Diabetes Mellitus (DM). Vaccination against influenza in DM patients may reduce influenza incidence and severity. ... -
SARS-CoV-2 infection triggers more potent antibody-dependent cellular cytotoxicity (ADCC) responses than mRNA-, vector-, and inactivated virus-based COVID-19 vaccines
Zedan, Hadeel T.; Smatti, Maria K.; Al-Sadeq, Duaa W.; Al Khatib, Hebah A.; Nicolai, Eleonora; Pieri, Massimo; Bernardini, Sergio; Hssain, Ali Ait; Taleb, Sara; Qotba, Hamda; Issa, Khodr; Abu Raddad, Laith J.; Althani, Asmaa A.; Nasrallah, Gheyath K.; Yassine, Hadi M.... more authors ... less authors ( Wiley , 2024 , Article)Neutralizing antibodies (NAbs) are elicited after infection and vaccination and have been well studied. However, their antibody-dependent cellular cytotoxicity (ADCC) functionality is still poorly characterized. Here, we ... -
The tale of an endemic shrimp’s exceptional osmoregulation and the ancient Athalassic mangrove oasis
Giraldes, Bruno W.; Boughattas, Sonia; Benslimane, Fatiha M.; Althani, Asmaa A.; Schubart, Christoph D.; Huber, Carla S.R.; Utz, Laura R.P.; Al-Khayat, Jassim A.A.; Sadooni, Fadhil N.; Amado, Enelise M.... more authors ... less authors ( Springer Nature , 2024 , Article)The hyperarid mangrove in the Middle East is characterised by the absence of rivers or freshwater inputs and is one of the most extreme settings of this ecosystem on Earth. Endemic to Qatar’s hyperarid mangroves, a Palaemon ... -
Viral metagenomics analysis of stool specimens from children with unresolved gastroenteritis in Qatar
Ghina, Hijazi; Dakroub, Fatima; Khoueiry, Pierre; El-Kurdi, Abdullah; Ezzeddine, Amani; Alkalamouni, Habib; Alansari, Khalid; Althani, Asmaa A.; Mathew, Shilu; AlKhatib, Hebah A.; Yassine, Hadi M.; Zaraket, Hassan... more authors ... less authors ( Elsevier , 2022 , Article)Acute gastroenteritis (AGE) is associated with significant global morbidity and mortality, especially among children under five years of age. Viruses are well established as etiologic agents of gastroenteritis since they ...