Browsing by Author "Elsayegh, Dina"
Now showing items 1-4 of 4
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Early Hepatic Gene Expression Profile of Lipid Metabolism of Mice on High Fat Diet after Treatment with Anti‐Obesity Drugs
Rizk, Nasser M; Saleh, Amena; Elsayegh, Dina; Algamal, Abdelrahman ( FASEB , 2020 , Conference Paper)Obesity is a multifactorial disorder of global scale. The liver plays a vital role in fat metabolism. Disorder of hepatic fat metabolism is associated with obesity and fatty liver disease. This study aimed to detect the ... -
The Expression of TBC1 Domain Family, Member 4 (TBC1D4) in Skeletal Muscles of Insulin-Resistant Mice in Response to Sulforaphane
Rizk, Nasser M; ElGamal, Abdelrahman; Elsayegh, Dina; Cakir, Isin; Ghamari-Langroudi, Masoud ( Endocrine Society , 2020 , Conference Paper)The Expression of TBC1 Domain Family, member 4 (TBC1D4) in Skeletal Muscles of Insulin-Resistant Mice in Response to Sulforaphane. Background: Obesity is commonly accompanied by impaired glucose homeostasis. Decreased ... -
Sulforaphane Downregulates Hepatic Fibroblast Growth Factor 21 (FGF21) of Diet Induced Obese Mice
Rizk, Nasser; Noureldin, Arwa; Galal, Aya; Mohamed, Omnia; ElGamal, Abdelrahman; Elsayegh, Dina... more authors ... less authors ( The Obesity Society , 2020 , Conference Paper)Background: Fibroblast growth factor 21 is a hormone-like protein that plays a critical role as an energy regulator. Sulforaphane (SFN) is expected to have potential therapeutic effects in treating obesity. This study aims ... -
Sulforaphane reduces obesity by reversing leptin resistance.
Çakır, Işın; Lining Pan, Pauline; Hadley, Colleen K; El-Gamal, Abdulrahman; Fadel, Amina; Elsayegh, Dina; Mohamed, Omnia; Rizk, Nasser M; Ghamari-Langroudi, Masoud... more authors ... less authors ( eLife Sciences Publications , 2022 , Article)The ascending prevalence of obesity in recent decades is commonly associated with soaring morbidity and mortality rates, resulting in increased health-care costs and decreased quality of life. A systemic state of stress ...