Browsing by Author "Al-Jaber, Hend"
Now showing items 1-7 of 7
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Age and sport intensity-dependent changes in cytokines and telomere length in elite athletes
Sellami, Maha; Al-Muraikhy, Shamma; Al-Jaber, Hend; Al-Amri, Hadaia; Al-Mansoori, Layla; Mazloum, Nayef A.; Donati, Francesco; Botre, Francesco; Elrayess, Mohamed A.... more authors ... less authors ( MDPI , 2021 , Article Review)Background: Exercise-associated immune response plays a crucial role in the aging process. The aim of this study is to investigate the effect of sport intensity on cytokine levels, oxidative stress markers and telomere ... -
Assessment of Serum Cytokines and Oxidative Stress Markers in Elite Athletes Reveals Unique Profiles Associated With Different Sport Disciplines
Sohail, Muhammad U.; Al-Mansoori, Layla; Al-Jaber, Hend; Georgakopoulos, Costas; Donati, Francesco; Botrè, Francesco; Sellami, Maha; Elrayess, Mohamed A.... more authors ... less authors ( Frontiers Media , 2020 , Article)© Copyright © 2020 Sohail, Al-Mansoori, Al-Jaber, Georgakopoulos, Donati, Botrè, Sellami and Elrayess. Objectives: Circulating cytokines and oxidative stress markers vary in response to different exercise regimens. This ... -
Comparing Methods for Induction of Insulin Resistance in Mouse 3T3-L1 Cells.
Al-Jaber, Hend; Al-Muraikhy, Shamma; Jabr, Aldana Jabr; Yousuf, Aisha; Anwardeen, Najeha; Elrayess, Mohamed; Al-Mansoori, Layla... more authors ... less authors ( Bentham Science Publishers , 2024 , Article)Cell culture plays a crucial role in addressing fundamental research questions, particularly in studying insulin resistance (IR) mechanisms. Multiple in vitro models are utilized for this purpose, but their technical ... -
GATA-3 as a potential therapeutic target for insulin resistance and type 2 diabetes mellitus.
Al-Jaber, Hend; Al-Mansoori, Layla; Elrayess, Mohamed A ( PubMed Central , 2020 , Article Review)Impaired adipogenesis plays an important role in the development of obesity-associated insulin resistance and type 2 diabetes as it leads to ectopic fat deposition. The anti-adipogenic transcription factor GATA-3 was ... -
Metabolomics of lean/overweight insulin resistant females reveals alterations in steroids and fatty acids.
Diboun, Ilhame; Al-Mansoori, Layla; Al-Jaber, Hend; Albagha, Omar; Elrayess, Mohamed A ( Endocrine Society , 2020 , Article)The global diabetes epidemic is largely attributed to obesity-triggered metabolic syndrome. However, the impact of insulin resistance (IR) prior to obesity on the high prevalence of diabetes and the molecular mediators ... -
Role of Inflammatory Cytokines, Growth Factors and Adipokines in Adipogenesis and Insulin Resistance
Al-Mansoori, Layla; Al-Jaber, Hend; Prince, Mohammad Shoaib; Elrayess, Mohamed A. ( Springer , 2021 , Article Review)Obesity, manifested by increased adiposity, represents a main cause of morbidity in the developed countries, causing increased risk of insulin resistance and type 2 diabetes mellitus. Recruitment of macrophages and activation ... -
Suppression of GATA-3 increases adipogenesis, reduces inflammation and improves insulin sensitivity in 3T3L-1 preadipocytes
Al-Mansoori, Layla; Al-Jaber, Hend; Madani, Aisha Y.; Mazloum, Nayef A.; Agouni, Abdelali; Ramanjaneya, Manjunath; Abou-Samra, Abdul Badi; Elrayess, Mohamed A.... more authors ... less authors ( Elsevier , 2020 , Article)© 2020 Impaired adipogenesis plays an important role in the development of obesity-associated insulin resistance and type 2 diabetes. Adipose tissue inflammation is a crucial mediator of this process. GATA-3 plays important ...