Browsing by Author "Karin-Kujundzic, Valentina"
Now showing items 1-6 of 6
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Dishevelled family proteins (DVL1-3) expression in intrauterine growth restriction (IUGR) placentas.
Sola, Ida Marija; Serman, Alan; Karin-Kujundzic, Valentina; Paic, Frane; Skrtic, Anita; Slatina, Paula; Kakarigi, Luka; Vranic, Semir; Serman, Ljiljana... more authors ... less authors ( BJBMS , 2020 , Article)Dishevelled family proteins (DVL1, DVL2, and DVL3) are cytoplasmic proteins that are involved in canonical and non-canonical Wnt signaling pathway during embryonic development. The role of DVL proteins in the placental ... -
Dishevelled family proteins in serous ovarian carcinomas: A clinicopathologic and molecular study
Karin-Kujundzic, Valentina; Kardum, Vedran; Marija Sola, Ida; Paic, Frane; Skrtic, Anita; Skenderi, Faruk; Serman, Alan; Nikuseva-Martic, Tamara; Vranic, Semir; Serman, Ljiljana... more authors ... less authors ( Wiley , 2019 , Article)Dishevelled family proteins (DVL1, DVL2 and DVL3) are cytoplasmic mediators involved in canonical and non-canonical Wnt signaling that are important for embryonic development. Since Wnt signaling promotes cell proliferation ... -
New insight into the role of PTCH1 protein in serous ovarian carcinomas.
Karin-Kujundzic, Valentina; Covarrubias-Pinto, Adriana; Skrtic, Anita; Vranic, Semir; Serman, Ljiljana ( Spandidos Publications , 2022 , Article)The Hedgehog (Hh) signaling pathway is essential for normal embryonic development, while its hyperactivation in the adult organism is associated with the development of various cancers. The role of the Hh signaling pathway ... -
Novel Epigenetic Biomarkers in Pregnancy-Related Disorders and Cancers
Karin-Kujundzic, Valentina; Sola, Ida Marija; Predavec, Nina; Potkonjak, Anamarija; Somen, Ema; Mioc, Pavao; Serman, Alan; Vranic, Semir; Serman, Ljiljana... more authors ... less authors ( MDPI , 2019 , Article)As the majority of cancers and gestational diseases are prognostically stage- and grade-dependent, the ultimate goal of ongoing studies in precision medicine is to provide early and timely diagnosis of such disorders. These ... -
The role of glycogen synthase kinase 3 (GSK3) in cancer with emphasis on ovarian cancer development and progression: A comprehensive review
Glibo, Mislav; Serman, Alan; Karin-Kujundzic, Valentina; Bekavac Vlatkovic, Ivanka; Miskovic, Berivoj; Vranic, Semir; Serman, Ljiljana... more authors ... less authors ( Association of Basic Medical Sciences of FBIH , 2021 , Article Review)Glycogen synthase kinase 3 (GSK3) is a monomeric serine-threonine kinase discovered in 1980 in a rat skeletal muscle. It has been involved in various cellular processes including embryogenesis, immune response, inflammation, ... -
WNT5A, β‑catenin and SUFU expression patterns, and the significance of microRNA deregulation in placentas with intrauterine growth restriction
Sola, Ida Marija; Karin-Kujundzic, Valentina; Paic, Frane; Lijovic, Lada; Glibo, Mislav; Serman, Nikola; Duic, Tihana; Skrtic, Anita; Kuna, Krunoslav; Vranic, Semir; Serman, Ljiljana... more authors ... less authors ( Spandidos Publications , 2023 , Article)Placental insufficiency is a common cause of intrauterine growth restriction (IUGR). It affects ~10% of pregnancies and increases fetal and neonatal morbidity and mortality. Although Wnt and Hh pathways are crucial for ...