Browsing by Author "MOUSA, HANAA"
Now showing items 1-8 of 8
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Acquisition of invasiveness by breast adenocarcinoma cells engages established hallmarks and novel regulatory mechanisms
Mousa, Hanaa; Elgamal, Mahmoud; Marei, Reham Ghazal; Souchelnytskyi, Nazariy; Lin, Kah-Wan.; Souchelnytskyi, Serhiy... more authors ... less authors ( International Institute of Anticancer Research , 2019 , Article)Background/Aim: Proteomics of invasiveness opens a window on the complexity of the metastasis-engaged mechanisms. The extend and types of this complexity require elucidation. Materials and Methods: Proteomics, immuno ... -
ApoM binds endotoxin contributing to neutralization and clearance by High Density Lipoprotein.
Mousa, Hanaa; Thanassoulas, Angelos; Zughaier, Susu M ( Elsevier , 2023 , Article)HDL possesses anti-inflammatory properties, however, the exact mechanism is not fully understood. Endotoxin is a potent inducers of TLR4 signaling, leading to inflammatory mediators' release. It has been estimated that ... -
Glycosylation is a novel TGF?1-independent post-translational modification of Smad2
Gotoh, Takaya; Iwahana, Hiroyuki; Kannan, Surya; Marei, Reham Ghazal; Mousa, Hanaa; Elgamal, Mahmoud; Souchelnytskyi, Serhiy... more authors ... less authors ( Elsevier B.V. , 2019 , Article)Smad2 is a crucial component of intracellular signaling by transforming growth factor-? (TGF?). Here we describe that Smad2 is glycosylated, which is a novel for Smad2 post-translational modification. We showed that the ... -
Hyperosmotic Stress Induces a Specific Pattern for Stress Granule Formation in Human-Induced Pluripotent Stem Cells
Salloum-Asfar, Salam; Engelke, Rudolf; Mousa, Hanaa; Goswami, Neha; Thompson, I. Richard; Palangi, Freshteh; Kamal, Kamal; Al-Noubi, Muna N.; Schmidt, Frank; Abdulla, Sara A.; Emara, Mohamed M.... more authors ... less authors ( Hindawi , 2021 , Article)Stress granules (SGs) are assemblies of selective messenger RNAs (mRNAs), translation factors, and RNA-binding proteins in small untranslated messenger ribonucleoprotein (mRNP) complexes in the cytoplasm. Evidence indicates ... -
Metabolomics Profiling of Vitamin D Status in Relation to Dyslipidemia
Mousa, Hanaa; Elrayess, Mohamed A.; Diboun, Ilhame; Jackson, Simon K.; Zughaier, Susu M. ( MDPI , 2022 , Article)Vitamin D deficiency is a global disorder associated with several chronic illnesses including dyslipidemia and metabolic syndrome. The impact of this association with both dyslipidemia and vitamin D deficiency on metabolomics ... -
Serum 25-Hydroxyvitamin D Is Inversely Associated with Monocyte Percentage to HDL Cholesterol Ratio among Young Healthy Adults in Qatar.
Mousa, Hanaa; Islam, Nazmul; Ganji, Vijay; Zughaier, Susu M ( MDPI , 2020 , Article)Low serum 25-hydroxyvitamin D [25(OH)D] is linked to an altered lipid profile. Monocytes play an important role in inflammation and lipid metabolism. Recently, monocyte percentage to HDL-cholesterol ratio (MHR) has emerged ... -
Serum 25-Hydroxyvitamin D Is Inversely Associated with Monocyte Percentage to HDL Cholesterol Ratio among Young Healthy Adults in Qatar.
Mousa, Hanaa; Islam, Nazmul; Ganji, Vijay; Zughaier, Susu M (2020)Low serum 25-hydroxyvitamin D [25(OH)D] is linked to an altered lipid profile. Monocytes play an important role in inflammation and lipid metabolism. Recently, monocyte percentage to HDL-cholesterol ratio (MHR) has emerged ... -
Vitamin D Immune Modulatory Effect on the Anti-inflammatory potential of HDL Associated Proteins
MOUSA, HANAA (2023 , Dissertation)Introduction: Vitamin D deficiency is highly prevalent in Qatar. Vitamin D exerts immune-modulatory effects leading to reduced inflammation. Therefore, vitamin D deficiency is associated with increased subclinical inflammation. ...