Browsing by Author "Kirti.S., Prabhu"
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RAS-mediated oncogenic signaling pathways in human malignancies
Khan, Abdul Q.; Kuttikrishnan, Shilpa; Kodappully S., Siveen; Kirti S., Prabhu; Shanmugakonar, Muralitharan; Al- Naemi, Hamda A.; Haris, Mohammad; Dermime, Said; Uddin, Shahab... more authors ... less authors ( Elsevier , 2018 , Article Review)Abnormally activated RAS proteins are the main oncogenic driver that governs the functioning of major signaling pathways involved in the initiation and development of human malignancies. Mutations in RAS genes and or its ... -
Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway
Kirti.S., Prabhu; Bhat, Ajaz A.; Siveen, Kodappully S.; Kuttikrishnan, Shilpa; Raza, Syed Shadab; Raheed, Thesni; Jochebeth, Anh; Khan, Abdul Q.; Chawdhery, M.Zafar; Haris, Mohammad; Kulinski, Michal; Dermime, Said; Steinhoff, Martin; Uddin, Shahab... more authors ... less authors ( Elsevier , 2021 , Article)Effective treatment of lung cancer remains a significant clinical challenge due to its multidrug resistance and side effects of the current treatment options. The high mortality associated with this malignancy indicates ...