تصفح حسب المؤلف "Althani, Asma"
-
Aspirin inhibits cancer stem cells properties and growth of glioblastoma multiforme through Rb1 pathway modulation.
Pozzoli, Giacomo; Marei, Hany E; Althani, Asma; Boninsegna, Alma; Casalbore, Patrizia; Marlier, Lionel N J L; Lanzilli, Giulia; Zonfrillo, Manuela; Petrucci, Giovanna; Rocca, Bianca; Navarra, Pierluigi; Sgambato, Alessandro; Cenciarelli, Carlo... more authors ... less authors ( Wiley , 2019 , Article)Several clinical studies indicated that the daily use of aspirin or acetylsalicylic acid reduces the cancer risk via cyclooxygenases (Cox-1 and Cox-2) inhibition. In addition, aspirin-induced Cox-dependent and -independent ... -
Chitosan gold nanoparticles for detection of amplified nucleic acids isolated from sputum
Tammam, Salma N.; Khalil, Mahmoud A.F.; Gawad, Eman Abdul; Althani, Asma; Zaghloul, Hosam; Azzazy, Hassan M.E.... more authors ... less authors ( Elsevier , 2017 , Article)A platform for nucleic acid detection employing chitosan and chitosan coated gold nanoparticles (AuNPs) was developed. Mycobacterium tuberculosis (MTB) was used as a model target. MTB DNA was extracted from sputum using ... -
Cholinergic and dopaminergic neuronal differentiation of human adipose tissue derived mesenchymal stem cells.
Marei, Hany El Sayed; El-Gamal, Aya; Althani, Asma; Afifi, Nahla; Abd-Elmaksoud, Ahmed; Farag, Amany; Cenciarelli, Carlo; Thomas, Caceci; Anwarul, Hasan... more authors ... less authors ( Wiley , 2018 , Article)Mesenchymal stem cells (MSCs) are multipotent cells that can differentiate into various cell types such as cartilage, bone, and fat cells. Recent studies have shown that induction of MSCs in vitro by growth factors including ... -
Differentiation of human olfactory bulb-derived neural stem cells toward oligodendrocyte.
Marei, Hany E; Shouman, Zeinab; Althani, Asma; Afifi, Nahla; A, Abd-Elmaksoud; Lashen, Samah; Hasan, Anwarul; Caceci, Thomas; Rizzi, Roberto; Cenciarelli, Carlo; Casalbore, Patrizia... more authors ... less authors ( Wiley , 2018 , Article)In the central nervous system (CNS), oligodendrocytes are the glial element in charge of myelin formation. Obtaining an overall presence of oligodendrocyte precursor cells/oligodendrocytes (OPCs/OLs) in culture from different ... -
Gene Expression Profiling of Embryonic Human Neural Stem Cells and Dopaminergic Neurons from Adult Human Substantia Nigra
Marei, Hany E.; Althani, Asma; Afifi, Nahla; Michetti, Fabrizio; Pescatori, Mario; Pallini, Roberto; Casalbore, Patricia; Cenciarelli, Carlo; Schwartz, Philip; Ahmed, Abd-Elmaksoud... more authors ... less authors ( Public Library of Science , 2011 , Article)Neural stem cells (NSC) with self-renewal and multipotent properties serve as an ideal cell source for transplantation to treat neurodegenerative insults such as Parkinson’s disease. We used Agilent’s and Illumina Whole ... -
Gene Expression Profiling of Embryonic Human Neural Stem Cells and Dopaminergic Neurons from Adult Human Substantia Nigra
Marei , Hany; Althani , Asma; Afifi , Nahla; Michetti , Fabricio; Pescatori , Mario; Pallini , Roberto; Casalbore , Patricia; Cenciarelli , Carlo; Schwartz , Philip; Ahmed , Abd-Elmaksoud... more authors ... less authors ( Hamad bin Khalifa University Press (HBKU Press) , 2012 , Conference Paper)Neural stem cells (NSC) with self-renewal and multipotent properties serve as an ideal cell source for transplantation to treat neurodegenerative insults such as Parkinson's disease. We used Agilent's and Illumina Whole ... -
Heart function and hemodynamic analysis for zebrafish embryos
Yalcin, Huseyin C.; Amindari, Armin; Butcher, Jonathan T.; Althani, Asma; Yacoub, Magdi ( John Wiley and Sons Inc. , 2017 , Article Review)The Zebrafish has emerged to become a powerful vertebrate animal model for cardiovascular research in recent years. Its advantages include easy genetic manipulation, transparency, small size, low cost, and the ability to ... -
Heart Function and Hemodynamics Analysis for Zebrafish Embryos
Yalcin, Huseyin C.; Amindari, Armin; Butcher, Jonathan T.; Althani, Asma; Yacoub, Magdi ( Wiley , 2017 , Article)The zebrafish has emerged to become a powerful vertebrate animal model for cardiovascular research in recent years. Its advantages include easy genetic manipulation, transparency, small size, low cost, and the ability to ... -
The Interference of Notch1 target Hes1 affects cell growth, differentiation and invasiveness of glioblastoma stem cells through modulation of multiple oncogenic targets
Cenciarelli, Carlo; E. Marei, Hany; Zonfrillo, Manuela; Casalbore, Patrizia; Felsani, Armando; Trevisi, Gianluca; Althani, Asma; Mangiola, Annunziato... more authors ... less authors ( Impact Journals , 2017 , Article)The invasive and lethal nature of Glioblastoma multiforme (GBM) necessitates the continuous identification of molecular targets and search of efficacious therapies to inhibit GBM growth. The GBM resistance to chemotherapy ... -
Nanodiagnostics for tuberculosis detection
El-Samadony, Hesham; Althani, Asma; Tageldin, Mohamed Awad; Azzazy, Hassan M.E. ( Taylor & Francis , 2017 , Article)Introduction Tuberculosis (TB) is a leading killer worldwide. End TB strategy aims at ending the TB epidemic by 2030. Early, accurate, and affordable diagnosis represents a cornerstone to achieve this goal. Innovative ... -
Qatar genome: Insights on genomics from the Middle East
Mbarek, Hamdi; Devadoss Gandhi, Geethanjali; Selvaraj, Senthil; Al-Muftah, Wadha; Badji, Radja; Al-Sarraj, Yasser; Saad, Chadi; Darwish, Dima; Alvi, Muhammad; Fadl, Tasnim; Yasin, Heba; Alkuwari, Fatima; Razali, Rozaimi; Aamer, Waleed; Abbaszadeh, Fatemeh; Ahmed, Ikhlak; Mokrab, Younes; Suhre, Karsten; Albagha, Omar; Fakhro, Khalid; Badii, Ramin; Ismail, Said I.; Althani, Asma... more authors ... less authors ( Wiley , 2022 , Article)Despite recent biomedical breakthroughs and large genomic studies growing momentum, the Middle Eastern population, home to over 400 million people, is underrepresented in the human genome variation databases. Here we ... -
Recent perspective on CAR and Fcγ-CR T cell immunotherapy for cancers: Preclinical evidence versus clinical outcomes.
Marei, Hany E; Althani, Asma; Caceci, Thomas; Arriga, Roberto; Sconocchia, Tommaso; Ottaviani, Alessio; Lanzilli, Giulia; Roselli, Mario; Caratelli, Sara; Cenciarelli, Carlo; Sconocchia, Giuseppe... more authors ... less authors ( Elsevier , 2019 , Article)The chimeric antigen receptor Tcell (CAR-T cell) immunotherapy currently represents a hot research trend and it is expected to revolutionize the field of cancer therapy. Promising outcomes have been achieved using CAR-T ... -
Sensitization to common food and inhalant allergens in children attending Allergy and Asthma Pediatric Clinic in Doha, Qatar
Kerkadi, Abdelhamid; Althani, Asma; Al-Boainain, Amina; Janahi, Ibrahim; Singh, Rajiv ( WFL Publisher , 2009 , Article)The prevalence of allergic diseases such as asthma, allergic rhinitis and atopic dermatitis have risen at an alarming rate throughout the world in the past 50 years. Sensitization to food (FA) and inhalant allergens (IA) ... -
A single tube system for the detection of Mycobacterium tuberculosis DNA using gold nanoparticles based FRET assay
Mansour, Amira; Tammam, Salma; Althani, Asma; Azzazy, Hassan M.E. ( Elsevier , 2017 , Article)Abstract The global combat against MTB is limited by challenges in accurate affordable detection. In this study, a rapid, affordable, single tube system for detection of unamplified MTB16s rDNA was developed. Utilizing a ... -
A single tube system for the detection of Mycobacterium tuberculosis DNA using gold nanoparticles based FRET assay
Amira, Mansour; Tammam, Salma; Althani, Asma; Azzazy, Hassan M.E. ( Elsevier , 2017 , Other)The global combat against MTB is limited by challenges in accurate affordable detection. In this study, a rapid, affordable, single tube system for detection of unamplified MTB16s rDNA was developed. Utilizing a AuNP based ...