تصفح حسب المؤلف "Yalcin, Huseyin"
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Assessment of Metal Organic Framework as Potential Drug Carriers in Cardiovascular Diseases
Al-Ansari, Dana E.; Mohamed, Nura A.; Marei, Isra; Yalcin, Huseyin; Abou-Saleh, Haissam ( Qatar University Press , 2020 , Poster)Background: Cardiovascular diseases (CVDs) are considered the major cause of death worldwide. Therapeutic delivery to the cardiovascular system may play an important role in the successful treatment of a variety of CVDs, ... -
ASSESSMENT OF ORDERING PRACTICES AT BIOMEDICAL RESEARCH CENTER (BRC)- METABOLIC RESEARCH LABORATORY (MRL)
Al-Ghoul, Manal M. (2021 , Professional Masters Project)Background: Assessment of the purchasing and ordering process in the Metabolic Research Laboratory (MRL) at the Biomedical Research Center (BRC) at Qatar University (QU) is a critical component of the quality management ... -
Development and In Vivo Testing of Smart Nanoparticles for Enhanced Anti-Cancer Activity and Reduced Cardiotoxicity Associated with Tyrosine Kinase Inhibitors
Yalcin, Huseyin; Al-Thani, Hissa; Shurbaji, Samar ( Qatar University Press , 2021 , Poster)Tyrosine kinase inhibitors (TKIs) are new generation of anti-cancer drugs with very high efficiency against cancer cells. However, TKIs are associated with severe cardiotoxicity limiting their clinical benefits. One TKI ... -
Direct Measurement of Vessel Pressure in Chicken Embryo during Development
Sukumaran, Vijayakumar; Abdelraheem, Rawia; Yalcin, Huseyin ( Qatar University Press , 2021 , Poster)Hemodynamic conditions play a critical role in embryonic cardiovascular development, and altered blood flow leads to congenital heart defects (CHD). Chicken embryos are commonly used as models of cardiac development, with ... -
Experimental and Biological Investigation of Hemodynamics-induced Injuries for Cardiovascular Disorders
Shurbaji, Samar Haroon; Yalcin, Huseyin ( Qatar University Press , 2021 , Poster)Introduction:Abdominal aortic aneurysm (AAA) is a degenerative disease process of the abdominal aorta that leads to a focal dilation and irreversible remodeling of the arterial wall. In this condition, the aortic vessel ... -
Human c-MYBPC3 RNA Targeted Therapy, Reversal of Hypertrophic Cardiomyopathy in the Zebrafish Model
Yalcin, Huseyin; Da'As, Sahar; Mohammed, Iman; Nasrallah, Gheyath; Al Suwaidi, Jasim; Yacoub, Magdi... more authors ... less authors ( Qscience. , 2016 , Conference Paper)Hypertrophic cardiomyopathy (HCM) is a serious heart disease and is defined as abnormal left ventricular (LV) wall thickening with diastolic dysfunction. HCM is an autosomal dominant monogenic disease caused by a mutation ... -
In Vivo Investigation of Cardiac Benefits of Sodium Glucose Cotransporter Inhibition Using the Zebrafish Model
Essa, Asma; Aldous, Noura; Benslimane, Fatiha; Yalcin, Huseyin ( Qatar University Press , 2020 , Poster)Type 2 diabetes mellitus (T2DM) affects >16% of adults in Qatar. Newly emerging class of antidiabetic drugs focuses on SGLT inhibition were observed to reduce CVDs risks in diabetic patients. Up to date, the mechanism ... -
Investigating the Cardiac Effects of New Generation Anti-Diabetic Drug EmpagliflozinUsing Zebrafish Embryo Model
Alkawari, Fatima; Ali, Wigdan; Benslimane, Fatiha; Yalcin, Huseyin ( Qatar University Press , 2020 , Poster)Type 2 diabetes mellitus (T2DM) affects >16% of adults in Qatar. Newly emerging class of anti-diabetic drugs focuses on SGLT inhibition were observed to reduce CVDs risks in diabetic patients. Up to date, the mechanism ... -
Investigating the effect of hyperglycemia on embryonic heart development using the chick embryo model
Benslimane, Fatiha; Ahmed, Muneera; Al-Thani, Hissa; Al Ser, Maha; Yalcin, Huseyin ( Qatar University Press , 2020 , Poster)Congenital heart defects (CHDs) represent the most common form of human birth defects. Maternal diabetes increases the risk of CHD by 3-5 folds. During heart development, little is known about the effects of high blood ... -
Investigating the efficacy of natural blood glucose lowering compounds in the prevention of congenital heart defects during maternal diabetes using the chick embryo
Haddad, Batoul; El-hashmi, Zainab; Yalcin, Huseyin; Benslimane, Fatiha; Hussain, Hana A. ( Qatar University Press , 2020 , Poster)Diabetes is a metabolic disorder that is characterized by hyperglycemia. Although there are several drugs available for diabetes, patients tend to follow natural remedies. However, the use of these natural remedies lacks ... -
Nitric Oxide Releasing Hydrogel Nanoparticles Decreases Epithelial Cell Injuries Associated With Airway Reopening
Shurbaji, Samar Haroon; Yalcin, Huseyin ( Qatar University Press , 2021 , Poster)Introduction: Acute respiratory distress syndrome (ARDS) is an acute inflammatory lung condition. It is characterized by disruption of gas exchange inside the alveoli, accumulation of protein edema, and an increase in lung ... -
THE ROLE OF P90 RIBOSOMAL S6 KINASE AND AUTOPHAGY IN SUNITINIB AND PONATINIB-INDUCED CARDIOTOXICITY
SULEIMAN, MUNA (2019 , Master Thesis)In recent years, the paradigm cancer management has shifted towards a targeted approach. Among the newly targeted anticancer therapies are ponatinib and sunitinib, small molecules tyrosine kinase inhibitors (TKIs), used ... -
The influence of shear stress on nanomaterial's uptake by MDA-231 breast cancer cells
Shurbaji, Samar; Elzatahry, Ahmed; Yalcin, Huseyin ( Qatar University Press , 2020 , Poster)Introduction: Recently, nanotechnology products have been used for a variety of applications including the medical field. Two dimensional (2D) nanomaterials have attracted a growing interest due to its unique properties ... -
Toxicity assessment of treated sewage effluent using the zebrafish embryo model
Nasser, Fatima Abdulwahab; Nasir, Halah Noor; Zakaria, Zain Zaki; Yalcin, Huseyin ( Qatar University Press , 2020 , Poster)Background: In a context of tremendous economic value, the management and protection of water resources in Qatar has long been a significant issue as part of the global wastewater management plan. The process is based on ... -
Unraveling Gene Expression Profiles of Cardiac Genes That Participate in Embryonic Development of Congenital Heart Defects Using Chick Embryo
Nasr, Amal; Omar, Aya; Alser, Maha; Yalcin, Huseyin; Benslimane, Fatiha ( Qatar University Press , 2020 , Poster)Hypoplastic left heart syndrome (HLHS) is a rare but serious subtype of congenital heart defects (CHDs) at which the hemodynamics are disturbed. In this project, HLHS was introduced surgically by left atrial ligation (LAL) ...