تصفح حسب المؤلف "Haris, Mohammad"
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1H magnetic resonance spectroscopy of 2H-to-1H exchange quantifies the dynamics of cellular metabolism in vivo
Rich, Laurie J; Bagga, Puneet; Wilson, Neil E; Schnall, Mitchell D; Detre, John A; Haris, Mohammad; Reddy, Ravinder... more authors ... less authors ( Nature Research , 2020 , Article)Quantitative mapping of the in vivo dynamics of cellular metabolism via non-invasive imaging contributes to our understanding of the initiation and progression of diseases associated with dysregulated metabolic processes. ... -
Association of genes with phenotype in autism spectrum disorder.
Nisar, Sabah; Hashem, Sheema; Bhat, Ajaz A; Syed, Najeeb; Yadav, Santosh; Azeem, Muhammad Waqar; Uddin, Shahab; Bagga, Puneet; Reddy, Ravinder; Haris, Mohammad... more authors ... less authors ( Impact Journals , 2019 , Article Review)Autism spectrum disorder (ASD) is a genetic heterogeneous neurodevelopmental disorder that is characterized by impairments in social interaction and speech development and is accompanied by stereotypical behaviors such as ... -
Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers
Santosh K., Yadav; Gupta, Rakesh K.; Hashem, Sheema; Nisar, Sabah; Azeem, Taha; Bhat, Ajaz A.; Syed, Najeeb; Garg, Ravindra K.; Venkatesh, Vimala; Kamal, Madeeha; Fakhro, Khalid; Frenneaux, Michael P.; Haris, Mohammad... more authors ... less authors ( Elsevier , 2020 , Article)IntroductionAntiretroviral therapy (ART) is considered the most effective way to prevent perinatal transmission of human immunodeficiency virus (HIV). However, there is little knowledge about the effect of ART on the brain ... -
Brain Microstructural Changes Support Cognitive Deficits in Normal Children Born to HIVinfected Mothers
Santosh Kumar Yadav, Rakesh K Gupta , Sabah N Ahmed , Sheema Hashem , Ajaz A Bhat , Ravindra K Garg , Vimala Venkatesh , Muhammad W Azeem , and Mohammad Haris.; Yadav, Santosh Kumar; Gupta, Rakesh K; Ahmed, Sabah N; Hashem, Sheema; Bhat, Ajaz A; Garg, Ravindra K; Venkatesh, Vimala; Azeem, Muhammad W; Haris, Mohammad... more authors ... less authors (2018 , Conference Proceedings)Synopsis In the current study, we evaluated the brain integrity [by mapping the fractional anisotropy (FA) and mean diffusivity (MD)] and neurocognitive performance (NP) in normal children (NCI) born to HIV-infected ... -
Changes in resting-state functional brain activity are associated with waning cognitive functions in HIV-infected children.
Yadav, Santosh K; Gupta, Rakesh K; Hashem, Sheema; Bhat, Ajaz A; Garg, Ravindra K; Venkatesh, Vimala; Gupta, Pradeep K; Singh, Alok K; Chaturvedi, Saurabh; Ahmed, Sabha Nisar; Azeem, Muhammad W; Haris, Mohammad... more authors ... less authors ( Elsevier , 2018 , Article)Delayed brain development in perinatally HIV-infected children may affect the functional brain activity and subsequently cognitive function. The current study evaluated the functional brain activity in HIV-infected children ... -
Chemokine-cytokine networks in the head and neck tumor microenvironment
Nisar, Sabah; Yousuf, Parvaiz; Masoodi, Tariq; Wani, Nissar A.; Hashem, Sheema; Singh, Mayank; Sageena, Geetanjali; Mishra, Deepika; Kumar, Rakesh; Haris, Mohammad; Bhat, Ajaz A.; Macha, Muzafar A.... more authors ... less authors ( MDPI , 2021 , Article Review)Head and neck squamous cell carcinomas (HNSCCs) are aggressive diseases with a dismal patient prognosis. Despite significant advances in treatment modalities, the five-year survival rate in patients with HNSCC has improved ... -
Claudin-1, A Double-Edged Sword in Cancer.
Bhat, Ajaz A; Syed, Najeeb; Therachiyil, Lubna; Nisar, Sabah; Hashem, Sheema; Macha, Muzafar A; Yadav, Santosh K; Krishnankutty, Roopesh; Muralitharan, Shanmugakonar; Al-Naemi, Hamda; Bagga, Puneet; Reddy, Ravinder; Dhawan, Punita; Akobeng, Anthony; Uddin, Shahab; Frenneaux, Michael P; El-Rifai, Wael; Haris, Mohammad... more authors ... less authors ( MDPI , 2020 , Article Review)Claudins, a group of membrane proteins involved in the formation of tight junctions, are mainly found in endothelial or epithelial cells. These proteins have attracted much attention in recent years and have been implicated ... -
Correction to: Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance (Molecular Cancer, (2020), 19, 1, (57), 10.1186/s12943-020-01175-9)
Bhat, Ajaz A.; Younes, Salma N.; Raza, Syed Shadab; Zarif, Lubna; Nisar, Sabah; Ahmed, Ikhlak; Mir, Rashid; Kumar, Sachin; Sharawat, Surender K.; Hashem, Sheema; Elfaki, Imadeldin; Kulinski, Michal; Kuttikrishnan, Shilpa; Prabhu, Kirti S.; Khan, Abdul Q.; Yadav, Santosh K.; El-Rifai, Wael; Zargar, Mohammad A.; Zayed, Hatem; Haris, Mohammad; Uddin, Shahab... more authors ... less authors ( BMC , 2020 , Other)Following the publication of the original article [1], authors have noticed that one of the authors, Syed Shadab Raza, was missing in the Authors’ Contributions section. Please see below updated section. -
Cross-talk between the microbiome and chronic inflammation in esophageal cancer: potential driver of oncogenesis
Sharma, Tarang; Gupta, Ashna; Chauhan, Ravi; Bhat, Ajaz A.; Nisar, Sabah; Hashem, Sheema; Akhtar, Sabah; Ahmad, Aamir; Haris, Mohammad; Singh, Mayank; Uddin, Shahab... more authors ... less authors ( Springer , 2022 , Article)Esophageal cancer (EC) is frequently considered a lethal malignancy and is often identified at a later stage. It is one of the major causes of cancer-related deaths globally. The conventional treatment methods like ... -
Cytokine- and chemokine-induced inflammatory colorectal tumor microenvironment: Emerging avenue for targeted therapy
Bhat, Ajaz A.; Nisar, Sabah; Singh, Mayank; Ashraf, Bazella; Masoodi, Tariq; Prasad, Chandra P.; Sharma, Atul; Maacha, Selma; Karedath, Thasni; Hashem, Sheema; Yasin, Syed Besina; Bagga, Puneet; Reddy, Ravinder; Frennaux, Michael P.; Uddin, Shahab; Dhawan, Punita; Haris, Mohammad; Macha, Muzafar A.... more authors ... less authors ( Wiley , 2022 , Article Review)Colorectal cancer (CRC) is a predominant life-threatening cancer, with liver and peritoneal metastases as the primary causes of death. Intestinal inflammation, a known CRC risk factor, nurtures a local inflammatory environment ... -
Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy
Bhat, A.A.; Bhat, Ajaz A.; Nisar, Sabah; Maacha, Selma; Carneiro-Lobo, Tatiana Correa; Akhtar, Sabah; Siveen, Kodappully Sivaraman; Wani, Nissar A.; Rizwan, Arshi; Bagga, Puneet; Singh, Mayank; Reddy, Ravinder; Uddin, Shahab; Grivel, Jean Charles; Chand, Gyan; Frenneaux, Michael P.; Siddiqi, Mushtaq A.; Bedognetti, Davide; El-Rifai, Wael; Macha, Muzafar A.; Haris, Mohammad... more authors ... less authors ( BMC , 2021 , Article Review)Esophageal cancer (EC) is a disease often marked by aggressive growth and poor prognosis. Lack of targeted therapies, resistance to chemoradiation therapy, and distant metastases among patients with advanced disease account ... -
Exploring Dysregulated Signaling Pathways in Cancer.
Nisar, Sabah; Hashem, Sheema; Yadav, Santosh K; Muralitharan, Sankavi; Therachiyil, Lubna; Sageena, Geetanjali; Al-Naemi, Hamda; Haris, Mohammad; Bhat, Ajaz A... more authors ... less authors ( Bentham Science Publishers , 2020 , Article Review)Cancer cell biology takes advantage of identifying diverse cellular signaling pathways that are disrupted in cancer. Signaling pathways are an important means of communication from the exterior of cell to intracellular ... -
Extracellular vesicles-mediated intercellular communication: roles in the tumor microenvironment and anti-cancer drug resistance.
Maacha, Selma; Bhat, Ajaz A; Jimenez, Lizandra; Raza, Afsheen; Haris, Mohammad; Uddin, Shahab; Grivel, Jean-Charles... more authors ... less authors ( Springer Verlag , 2019 , Article)The tumor microenvironment represents a complex network, in which tumor cells not only communicate with each other but also with stromal and immune cells. Current research has demonstrated the vital role of the tumor ... -
Functional In Vivo Imaging of Tumors.
Haris, Mohammad; Nisar, Sabah; Hashem, Sheema; Bhat, Ajaz A; Yadav, Santosh; Shanmugakonar, Muralitharan; Al-Naemi, Hamda; Bagga, Puneet; Uddin, Shahab; Reddy, Ravinder... more authors ... less authors ( Springer , 2020 , Book chapter)Noninvasive imaging of functional and molecular changes in cancer has become an indispensable tool for studying cancer in vivo. Targeting the functional and molecular changes in cancer imaging provides a platform for the ... -
Genetic and Neuroimaging Approaches to Understanding Post-Traumatic Stress Disorder.
Nisar, Sabah; Bhat, Ajaz A; Hashem, Sheema; Syed, Najeeb; Yadav, Santosh K; Uddin, Shahab; Fakhro, Khalid; Bagga, Puneet; Thompson, Paul; Reddy, Ravinder; Frenneaux, Michael P; Haris, Mohammad... more authors ... less authors ( MDPI , 2020 , Article Review)Post-traumatic stress disorder (PTSD) is a highly disabling condition, increasingly recognized as both a disorder of mental health and social burden, but also as an anxiety disorder characterized by fear, stress, and ... -
Genetic variations influence brain changes in patients with attention-deficit hyperactivity disorder
Yadav, Santosh K.; Bhat, Ajaz A.; Hashem, Sheema; Nisar, Sabah; Kamal, Madeeha; Syed, Najeeb; Temanni, Mohamed Ramzi; Gupta, Rakesh K.; Kamran, Saddat; Azeem, Muhammad Waqar; Srivastava, Amit K.; Bagga, Puneet; Chawla, Sanjeev; Reddy, Ravinder; Frenneaux, Michael P.; Fakhro, Khalid; Haris, Mohammad... more authors ... less authors ( Springer Nature , 2021 , Article Review)Attention-deficit hyperactivity disorder (ADHD) is a neurological and neurodevelopmental childhood-onset disorder characterized by a persistent pattern of inattentiveness, impulsiveness, restlessness, and hyperactivity. ... -
Genetics of glutamate and its receptors in autism spectrum disorder
Nisar, Sabah; Bhat, Ajaz A.; Masoodi, Tariq; Hashem, Sheema; Akhtar, Sabah; Ali, Tayyiba Akbar; Amjad, Sara; Chawla, Sanjeev; Bagga, Puneet; Frenneaux, Michael P.; Reddy, Ravinder; Fakhro, Khalid; Haris, Mohammad... more authors ... less authors ( Springer Nature , 2022 , Article Review)Autism spectrum disorder (ASD) is a neurodevelopmental impairment characterized by deficits in social interaction skills, impaired communication, and repetitive and restricted behaviors that are thought to be due to altered ... -
Genetics of structural and functional brain changes in autism spectrum disorder.
Hashem, Sheema; Nisar, Sabah; Bhat, Ajaz A; Yadav, Santosh Kumar; Azeem, Muhammad Waqar; Bagga, Puneet; Fakhro, Khalid; Reddy, Ravinder; Frenneaux, Michael P; Haris, Mohammad... more authors ... less authors ( Springer Nature , 2020 , Article Review)Autism spectrum disorder (ASD) is a neurological and developmental disorder characterized by social impairment and restricted interactive and communicative behaviors. It may occur as an isolated disorder or in the context ... -
Insights Into the Role of CircRNAs: Biogenesis, Characterization, Functional, and Clinical Impact in Human Malignancies
Nisar, Sabah; Bhat, Ajaz A.; Singh, Mayank; Karedath, Thasni; Rizwan, Arshi; Hashem, Sheema; Bagga, Puneet; Reddy, Ravinder; Jamal, Farrukh; Uddin, Shahab; Chand, Gyan; Bedognetti, Davide; El-Rifai, Wael; Frenneaux, Michael P.; Macha, Muzafar A.; Ahmed, Ikhlak; Haris, Mohammad... more authors ... less authors ( Frontiers Media , 2021 , Article Review)Circular RNAs (circRNAs) are an evolutionarily conserved novel class of non-coding endogenous RNAs (ncRNAs) found in the eukaryotic transcriptome, originally believed to be aberrant RNA splicing by-products with decreased ... -
Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments
Lone, Saife N.; Nisar, Sabah; Masoodi, Tariq; Singh, Mayank; Rizwan, Arshi; Hashem, Sheema; El-Rifai, Wael; Bedognetti, Davide; Batra, Surinder K.; Haris, Mohammad; Bhat, Ajaz A.; Macha, Muzafar A.... more authors ... less authors ( BMC , 2022 , Article Review)Over the past decade, invasive techniques for diagnosing and monitoring cancers are slowly being replaced by non-invasive methods such as liquid biopsy. Liquid biopsies have drastically revolutionized the field of clinical ...