Browsing by Author "Lv, Guohua"
Now showing items 1-2 of 2
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Ginsenoside Rb1 inhibits fibrillation and toxicity of alpha-synuclein and disaggregates preformed fibrils
Ardah, Mustafa T.; Paleologou, Katerina E.; Lv, Guohua; Menon, Sindhu A.; Abul Khair, Salema B.; Lu, Jia-Hong; Safieh-Garabedian, Bared; Al-Hayani, Abdulmonem A.; Eliezer, David; Li, Min; El-Agnaf, Omar M.A.... more authors ... less authors ( Elsevier , 2015 , Article)Compelling evidence indicates that α-synuclein (α-syn) aggregation plays a central role in the pathogenesis of Parkinson's disease (PD) and other synucleinopathies. Identification of compounds that inhibit or reverse the ... -
Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts.
Ardah, Mustafa T; Ghanem, Simona S; Abdulla, Sara A; Lv, Guohua; Emara, Mohamed M; Paleologou, Katerina E; Vaikath, Nishant N; Lu, Jia-Hong; Li, Min; Vekrellis, Konstantinos; Eliezer, David; El-Agnaf, Omar M A... more authors ... less authors ( BMC , 2020 , Article)Recent studies indicated that seeded fibril formation and toxicity of α-synuclein (α-syn) play a main role in the pathogenesis of certain diseases including Parkinson's disease (PD), multiple system atrophy, and dementia ...