Browsing by Author "Khan, Shahzeb"
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Efficient design to fabricate smart Lumefantrine nanocrystals using DENA® particle engineering technology: Characterisation, in vitro and in vivo antimalarial evaluation and assessment of acute and sub-acute toxicity
Syed Muhammad, Hassan Shah; Mukarram Shah, Syed Muhammad; Khan, Shahzeb; Ullah, Farhat; Ali Shah, Syed Wadood; Ghias, Mehreen; Shahid, Muhammad; Smyth, Hugh DC.; Hussain, Zahid; Sohail, Muhammad; Elhissi, Abdelbary; Isreb, Mohammad... more authors ... less authors ( Elsevier , 2020 , Article)Nanocrystalization technologies have a great potential to substantially increase solubility as well as alleviate the erratic bioavailability behaviour of a range of poorly water soluble drugs. The aim of the current study ... -
Norfloxacin loaded lipid polymer hybrid nanoparticles for oral administration: Fabrication, characterization, in silico modelling and toxicity evaluation
Khan, Muhammad A.; Khan, Shahzeb; Kazi, Mohsin; Alshehri, Sultan M.; Shahid, Muhammad; Khan, Shafi U.; Hussain, Zahid; Sohail, Muhammad; Shafique, Muhammad; Hamid, Hajra A.; Kamran, Mahwish; Elhissi, Abdelbary; Wasim, Muhammad; Thu, Hnin E.... more authors ... less authors ( MDPI , 2021 , Article)Norfloxacin (NOR), widely employed as an anti-bacterial drug, has poor oral bioavailability. Nano based drug delivery systems are widely used to overcome the existing oral bioavailability challenges. Lipid–Polymer Hybrid ... -
Piroxicam loaded polymer hybrid microspheres based tablets with modified release kinetics: Development, characterization and in vivo evaluation
Hamid, Hajra Afeera; Khan, Shahzeb; Shah, Syed Muhammad Noor; Asghar, Muhammad.; Shahid, Muhammad; Hussain, Zahid; Sohail, Muhammad; Khan, Barkat Ali; Amin, Fazli; Jan, Syed Umer; Elhissi, Abdelbary; Shah, Syed Muhammad Hassan; Minhas, Muhammad Usman; Shah, Syed Wadood Ali; Ahmad, Naveed... more authors ... less authors ( Pakistan Journal of Pharmaceutical Sciences , 2021 , Article)Piroxicam (PC) is a non-steroidal anti-inflammatory drug characterized by poor aqueous solubility and reported to cause and impart crucial GIT irritation, bleeding, peptic and duodenal ulcer. Engineering of PC ... -
Recent advancements in stimuli responsive drug delivery platforms for active and passive cancer targeting
Rahim, Muhammad A.; Jan, Nasrullah; Khan, Safiullah; Shah, Hassan; Madni, Asadullah; Khan, Arshad; Jabar, Abdul; Khan, Shahzeb; Elhissi, Abdelbary; Hussain, Zahid; Aziz, Heather C.; Sohail, Muhammad; Khan, Mirazam; Thu, Hnin E.... more authors ... less authors ( MDPI AG , 2021 , Article Review)The tumor-specific targeting of chemotherapeutic agents for specific necrosis of cancer cells without affecting the normal cells poses a great challenge for researchers and scientists. Though extensive research has been ...