Browsing by Author "Shkoor, Mohanad"
Now showing items 1-9 of 9
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DMAP-Catalyzed Reaction of Diethyl 1,3-Acetonedicarboxylate with 2-Hydroxybenzylideneindenediones: Facile Synthesis of Fluorenone-Fused Coumarins
Shkoor, Mohanad; Bayari, Raghad ( Thieme Gruppe , 2021 , Other)The base-catalyzed reaction of diethyl 1,3-acetonedicarboxylate with 2-hydroxybenzylidene indenediones was studied. The reaction provides a facile and expeditious protocol for the synthesis of natural product inspired ... -
l-Proline-Catalyzed Three-Component Reaction of 4-Chloro-3-formylcoumarin, Sodium Sulfide, and α-Halo Ketones: A Direct Approach to Thieno[3,2- c ]coumarins
Thotathil, Vandana; Al-Zoubi, Raed M.; Sawali, Mona; Su, Haw Lih; Shkoor, Mohanad ( Georg Thieme Verlag KG , 2023 , Other)A new protocol for the synthesis of thieno[3,2-c]coumarins is disclosed. In this method, a 3-formyl-2-oxo-2H-chromene-4-thiolate anion is generated in situ by treatment of 4-chloro-3-formylcoumarin with sodium sulfide. ... -
Mechanochemical arylative detrifluoromethylation of trifluoromethylarenes
Mkrtchyan, Satenik; Shkoor, Mohanad; Sarfaraz, Sehrish; Ayub, Khurshid; Iaroshenko, Viktor O. ( Royal Society of Chemistry , 2023 , Article)The stoichiometric defluorinative functionalization of ArCF3 is a conceptually appealing research target. It enables the challenging late-stage functionalization of CF3-containing aromatic molecules and contributes to the ... -
Mechanochemical Conversion of Aromatic Amines to Aryl Trifluoromethyl Ethers
Jakubczyk, Michał; Mkrtchyan, Satenik; Shkoor, Mohanad; Lanka, Suneel; Budzák, Šimon; Iliaš, Miroslav; Skoršepa, Marek; Iaroshenko, Viktor O.... more authors ... less authors ( American Chemical Society , 2022 , Article)Increased interest in the trifluoromethoxy group in organic synthesis and medicinal chemistry has induced a demand for new, selective, general, and faster methods applicable to natural products and highly functionalized ... -
Mechanochemical Defluorinative Arylation of Trifluoroacetamides: An Entry to Aromatic Amides
Mkrtchyan, Satenik; Shkoor, Mohanad; Phanindrudu, Mandalaparthi; Medved′, Miroslav; Sevastyanova, Olena; Iaroshenko, Viktor O.... more authors ... less authors ( American Chemical Society , 2022 , Article)The amide bond is prominent in natural and synthetic organic molecules endowed with activity in various fields. Among a wide array of amide synthetic methods, substitution on a pre-existing (O)C-N moiety is an underexplored ... -
Mechanochemical Transformation of CF3 Group: Synthesis of Amides and Schiff Bases
Mkrtchyan, Satenik; Jakubczyk, Michał; Lanka, Suneel; Yar, Muhammad; Ayub, Khurshid; Shkoor, Mohanad; Pittelkow, Michael; Iaroshenko, Viktor O.... more authors ... less authors ( Wiley , 2021 , Article)We communicate two mild, solvent-free mechanochemical coupling transformations of CF3 group with nitro compounds into amides or Schiff bases employing Ytterbia as a catalyst. This process proceeds via C−F bond activation, ... -
Spectrofluorometric investigations on the solvent effects on the photocyclization reaction of diclofenac
Abdulilah Dawoud, Bani-Yaseen; Al-Zoubi, Raed M.; Shkoor, Mohanad ( Elsevier , 2023 , Article)The solvent effects on the photochemical conversion rate of the photosensitizing drug diclofenac (DCF) were investigated using steady-state fluorescence spectroscopy. The spectral information obtained for the photochemical ... -
Synthesis of 5-oxo-5H-chromeno[3,4-c]pyridine-1-carbonitriles and features of their NMR spectra
Shkoor, Mohanad; Su, Haw‐Lih; Ahmed, Suzan; Hegazy, Sarah ( Wiley , 2019 , Article)Two different methods leading to 5-oxo-5H-chromeno[3,4-c]pyridine-1-carbonitriles were investigated. Reactions of 3-aminocrotonirile with substituted salicylaldehydes provided 5-oxo-5H-chromeno[3,4-c]pyridine-1-carbonitriles ... -
Unusual product from the acid-catalyzed one-pot, multicomponent reaction of thiocarbohydrazide, aldehydes, and phenacyl bromides
Shkoor, Mohanad; Al-Abade, Ayahtallah; Aleteiwib, Ibtesam; Al-Talib, Mahmoud; Tashtoush, Hasan ( Taylor & Francis , 2017 , Article)A one-pot, three-component protocol for the synthesis of novel five-membered thiazole ring bonded to two hydrazone motifs is described. The acid-catalyzed reaction of one equivalent of thiocarbohydrazide, two equivalents ...