تصفح حسب المؤلف "El-Hashim, Ahmed Z."
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Ang-(1-7)/ MAS1 receptor axis inhibits allergic airway inflammation via blockade of Src-mediated EGFR transactivation in a murine model of asthma.
El-Hashim, Ahmed Z; Khajah, Maitham A; Babyson, Rhema S; Renno, Waleed M; Ezeamuzie, Charles I; Benter, Ibrahim F; Akhtar, Saghir... more authors ... less authors ( PLoS ONE , 2019 , Article)The angiotensin-(1-7) [Ang-(1-7)]/MAS1 receptor signaling axis is a key endogenous anti-inflammatory signaling pathway. However, the mechanisms by which its mediates the anti-inflammatory effects are not completely understood. ... -
Chronic administration of nano-sized PAMAM dendrimers in vivo inhibits EGFR-ERK1/2-ROCK signaling pathway and attenuates diabetes-induced vascular remodeling and dysfunction.
Akhtar, Saghir; Chandrasekhar, Bindu; Yousif, Mariam Hm; Renno, Waleed; Benter, Ibrahim F; El-Hashim, Ahmed Z... more authors ... less authors ( Elsevier , 2019 , Article)We investigated whether chronic administration of nano-sized polyamidoamine (PAMAM) dendrimers can have beneficial effects on diabetes-induced vascular dysfunction by inhibiting the epidermal growth factor receptor ...