Browsing by Author "Al-Muraikhy, Shamma"
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Age and sport intensity-dependent changes in cytokines and telomere length in elite athletes
Sellami, Maha; Al-Muraikhy, Shamma; Al-Jaber, Hend; Al-Amri, Hadaia; Al-Mansoori, Layla; Mazloum, Nayef A.; Donati, Francesco; Botre, Francesco; Elrayess, Mohamed A.... more authors ... less authors ( MDPI , 2021 , Article Review)Background: Exercise-associated immune response plays a crucial role in the aging process. The aim of this study is to investigate the effect of sport intensity on cytokine levels, oxidative stress markers and telomere ... -
Comparing Methods for Induction of Insulin Resistance in Mouse 3T3-L1 Cells.
Al-Jaber, Hend; Al-Muraikhy, Shamma; Jabr, Aldana Jabr; Yousuf, Aisha; Anwardeen, Najeha; Elrayess, Mohamed; Al-Mansoori, Layla... more authors ... less authors ( Bentham Science Publishers , 2024 , Article)Cell culture plays a crucial role in addressing fundamental research questions, particularly in studying insulin resistance (IR) mechanisms. Multiple in vitro models are utilized for this purpose, but their technical ... -
Effect of sera from elite athletes on cytokine secretion and insulin signaling in preadipocytes and skeletal muscle cells
Alheidous, Sara; Al-Muraikhy, Shamma; Rizk, Nasser; Sellami, Maha; Donati, Francesco; Botre, Francesco; Al-Mansoori, Layla; Elrayess, Mohamed A.... more authors ... less authors ( Frontiers Media , 2022 , Article)Introduction: The immunomodulatory effect of physical activity can impact insulin signaling differentially in adipose tissues and skeletal muscle cells, depending on sport intensity. In this study, the effect of serum from ... -
High Endurance Elite Athletes Show Age-dependent Lower Levels of Circulating Complements Compared to Low/Moderate Endurance Elite Athletes
Al-Muraikhy, S.; Al-Muraikhy, Shamma; Ramanjaneya, Manjunath; Dömling, Alexander S.; Bettahi, Ilham; Donati, Francesco; Botre, Francesco; Abou-Samra, Abdul Badi; Sellami, Maha; Elrayess, Mohamed A.... more authors ... less authors ( Frontiers Media , 2021 , Article)Introduction: Aerobic exercise activates the complement system in the peripheral blood. However, the effect of age and high intensity endurance training on the levels of circulating complements and sassociated inflammatory ... -
In Vitro and In Vivo Validation of GATA-3 Suppression for Induction of Adipogenesis and Improving Insulin Sensitivity
Al-Jaber, Hend; Mohamed, Nura A.; Govindharajan, Vijay K.; Taha, Samir; John, Jomon; Halim, Sharique; Alser, Maha; Al-Muraikhy, Shamma; Anwardeen, Najeha Rizwana; Agouni, Abdelali; Elhissi, Abdelbary; Al-Naemi, Hamda A.; Al-Mansoori, Layla; Elrayess, Mohamed A.... more authors ... less authors ( MDPI , 2022 , Article)Impaired adipogenesis is associated with the development of insulin resistance and an increased risk of type 2 diabetes (T2D). GATA Binding Protein 3 (GATA3) is implicated in impaired adipogenesis and the onset of insulin ... -
Metabolic Signature of Leukocyte Telomere Length in Elite Male Soccer Players
Al-Muraikhy, Shamma; Sellami, Maha; Domling, Alexander S; Rizwana, Najeha; Agouni, Abdelali; Al-Khelaifi, Fatima; Donati, Francesco; Botre, Francesco; Diboun, Ilhame; Elrayess, Mohamed A... more authors ... less authors ( Frontiers Media , 2021 , Article)Biological aging is associated with changes in the metabolic pathways. Leukocyte telomere length (LTL) is a predictive marker of biological aging; however, the underlying metabolic pathways remain largely unknown. The aim ...