Browsing by Author "Calver, Brian L."
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Life-threatening arrhythmogenic CaM mutations disrupt CaM binding to a distinct RyR2 CaM-binding pocket
Angelos, Thanassoulas; Vassilakopoulou, Vyronia; Calver, Brian L.; Buntwal, Luke; Smith, Adrian; Lai, Christopher; Kontogianni, Iris; Livaniou, Evangelia; Nounesis, George; Lai, F. Anthony; Nomikos, Michail... more authors ... less authors ( Elsevier , 2023 , Article)Calmodulin (CaM) modulates the activity of several proteins that play a key role in excitation-contraction coupling (ECC). In cardiac muscle, the major binding partner of CaM is the type-2 ryanodine receptor (RyR2) and ...