تصفح حسب المؤلف "n 89181679"
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Chapter Four Controlling cell proliferation by targeting cyclin-dependent kinase 6 using drug repurposing approach
N., Madhana Priya; Balasundaram, Ambritha; Sidharth Kumar, N.; Udhaya Kumar, S.; Thirumal Kumar, D.; Magesh, R.; Zayed, Hatem; George Priya Doss, C.... more authors ... less authors ( Elsevier , 2023 , Book chapter)Cyclin-dependent kinase 6 (CDK6) is an essential kinase in cell cycle progression, which is a viable target for inhibitors in various malignancies, including breast cancer. This study aimed to virtually screen efficient ... -
Molecular insights of the G2019S substitution in LRRK2 kinase domain associated with Parkinson's disease: A molecular dynamics simulation approach.
Agrahari, Ashish Kumar; Doss, George Priya C; Siva, R; Magesh, R; Zayed, Hatem ( Elsevier , 2019 , Article)The G2019S substitution in the Leucine-rich repeat kinase 2 (LRRK2) is significantly associated with Parkinson's disease (PD). This substitution was identified in both familial and sporadic forms of PD with a higher ... -
A review of novel coronavirus disease (COVID-19): based on genomic structure, phylogeny, current shreds of evidence, candidate vaccines, and drug repurposing
Kumar, S. Udhaya; Priya, N. Madhana; Nithya, S. R.; Kannan, Priyanka; Jain, Nikita; Kumar, D. Thirumal; Magesh, R.; Younes, Salma; Zayed, Hatem; Doss, C. George Priya... more authors ... less authors ( Springer Verlag , 2021 , Article Review)Coronavirus disease (COVID-19) pandemic is instigated by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). As of March 13, 2021, more than 118.9 million cases were infected with COVID-19 worldwide. SARS-CoV-2 ...