تصفح حسب المؤلف "n 2005069336"
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Allergenicity of roasted peanuts treated with a non-human digestive protease
Yu, Jianmei; Hernandez, Michelle; Li, Hao; Goktepe, Ipek; Robinette, Carole; Auerbach, Amy; Peden, David; Ahmedna, Mohamed... more authors ... less authors ( Elsevier Ltd , 2015 , Article)Peanut allergy is a severe and lifelong type of food allergy triggered by allergenic proteins and peptides in peanuts. This study investigated the effects of ultrasound-assisted alcalase treatment on the concentrations of ... -
Bioactive compounds isolated from apple, tea, and ginger protect against dicarbonyl induced stress in cultured human retinal epithelial cells
Sampath, Chethan; Zhu, Yingdong; Sang, Shengmin; Ahmedna, Mohamed ( Elsevier , 2016 , Article)Abstract BackgroundMethylglyoxal (MGO) is known to be a major precursor of advanced glycation end products (AGEs) which are linked to diabetes and its related complications. Naturally occurring bioactive compounds could ... -
Bioavailability and hypolipidemic effects of peanut skin polyphenols
Bansode, Rishipal R.; Randolph, Priscilla; Ahmedna, Mohamed; Williams, Leonard L.; Yu, Jianmei ( Mary Ann Liebert, Inc. , 2015 , Article)Peanut skin is a rich source of polyphenols, such as proanthocyanidins. Peanut skin proanthocyanidins mainly consist of a subgroup called procyanidins. Peanut-based procyanidins contain oligomers of both type A and type ... -
Green tea epigallocatechin 3-gallate alleviates hyperglycemia and reduces advanced glycation end products via nrf2 pathway in mice with high fat diet-induced obesity
Sampath, Chethan; Rashid, Muhammed Raihan; Sang, Shengmin; Ahmedna, Mohamed ( Elsevier , 2017 , Article)Abstract Epigallocatechin 3-gallate (EGCG) from green tea may reduce plasma glucose and alleviate complications of diabetes by attenuating advanced glycation end products (AGEs) formation. We hypothesized that EGCG would ... -
In vitro and in vivo inhibition of aldose reductase and advanced glycation end products by phloretin, epigallocatechin 3-gallate and [6]-gingerol
Sampath, Chethan; Sang, Shengmin; Ahmedna, Mohamed ( Elsevier , 2016 , Article)Abstract Hyperglycemic stress activates polyol pathway and aldose reductase (AR) key enzyme responsible for generating secondary complications during diabetes. In this study the therapeutic potential of phloretin, ... -
The potential of papain and alcalase enzymes and process optimizations to reduce allergenic gliadins in wheat flour
Li, Ying; Yu, Jianmei; Goktepe, Ipek; Ahmedna, Mohamed ( Elsevier Ltd , 2016 , Article)The objectives of this study were to select effective enzymes that catalyze the hydrolysis of allergenic proteins, gliadins, in wheat flour and to optimize the enzymatic treatment conditions. Six proteases were tested. ... -
Specific bioactive compounds in ginger and apple alleviate hyperglycemia in mice with high fat diet-induced obesity via Nrf2 mediated pathway
Sampath, Chethan; Rashid, Muhammed; Sang, Shengmin; Ahmedna, Mohamed ( Elsevier , 2017 , Article)Prolonged hyperglycemia activates the formation of advanced glycation end-products (AGEs). Major dicarbonyl compounds such as methylglyoxal or glyoxal are found to be the main precursors of AGEs and N(e)-(carboxymethyl)lysine ... -
Tea flavanols block advanced glycation of lens crystallins induced by dehydroascorbic acid
Zhu, Yingdong; Zhao, Yantao; Wang, Pei; Ahmedna, Mohamed; Ho, Chi-Tang; Sang, Shengmin... more authors ... less authors ( American Chemical Society , 2015 , Article)Growing evidence has shown that ascorbic acid (ASA) can contribute to protein glycation and the formation of advanced glycation end products (AGEs), especially in the lens. The mechanism by which ascorbic acid can cause ... -
A weight-management camp followed by weekly after-school lifestyle education sessions as an obesity intervention for Qatari children: a prospective cohort study
Taylor, Michael James; Vlaev, Ivo; Taylor, David, 1958-; Gately, Gately; Ahmedna, Mohamed; Kerkadi, Abdelhamid; Lothian, Jackie; Alsaadi, Aziza; Al-Kuwari, Mohamed; Gholoum, Suhaila; Al-Kuwari, Hanan; Darzi, Ara... more authors ... less authors ( Elsevier , 2015 , Conference Paper)Background Weight-management camp interventions for obese children are eff ective for short-term weight loss. However, there is little evidence indicating how gains made with such interventions can be maintained in the ...