Browsing by Author "Xu, Chang"
Now showing items 1-20 of 24
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Arcsine-based transformations for meta-analysis of proportions: Pros, cons, and alternatives
( Wiley Open Access , 2020 , Article)© 2020 The Authors. Health Science Reports published by Wiley Periodicals LLC. Meta-analyses have been increasingly used to synthesize proportions (eg, disease prevalence) from multiple studies in recent years. Arcsine-based ... -
Comparison of immunogenicity and safety of licensed Japanese encephalitis vaccines: A systematic review and network meta-analysis
( Elsevier , 2021 , Article Review)IntroductionAnnually more than 100,000 Japanese encephalitis (JE) cases and 25,000 deaths worldwide are caused by JE virus infection. More than 15 JE vaccines are currently in use worldwide. It is unknown whether any of ... -
Controversy and Debate: Questionable utility of the relative risk in clinical research: Paper 1: A call for change to practice
( Elsevier , 2020 , Article)Background and Objectives In clinical trials, the relative risk or risk ratio (RR) is a mainstay of reporting of the effect magnitude for an intervention. The RR is the ratio of the probability of an outcome in an ... -
Double-zero-event studies matter: A re-evaluation of physical distancing, face masks, and eye protection for preventing person-to-person transmission of COVID-19 and its policy impact
( Elsevier , 2021 , Article)In a recent timely systematic review, Chu et al. [1] assessed the effectiveness of face masks, eye protection, and physical distancing for preventing COVID-19. Because the sample sizes are not large, especially in some ... -
Empirical Comparisons of 12 Meta-analysis Methods for Synthesizing Proportions of Binary Outcomes
( Springer , 2021 , Article)Background: Meta-analysis is increasingly used to synthesize proportions (e.g., disease prevalence). It can be implemented with widely used two-step methods or one-step methods, such as generalized linear mixed models ... -
The Freeman–Tukey double arcsine transformation for the meta-analysis of proportions: Recent criticisms were seriously misleading
( John Wiley & Sons, Ltd , 2021 , Article)Pooling of proportions in meta-analysis are used to get better and more precise estimates of disease frequency, including cumulative incidence or prevalence. Meta-analysis is of course only useful when there are a limited ... -
Immunogenicity after pre- and post-exposure rabies vaccination: A systematic review and dose-response meta-analysis
( Elsevier , 2021 , Article)There are a myriad of vaccine schedules for rabies pre- (PrEP) and post-exposure prophylaxis (PEP) that differ in the number and timedoses, number of visits, length of schedule, and route of administration. The objective ... -
Laplace approximation, penalized quasi-likelihood, and adaptive Gauss-Hermite quadrature for generalized linear mixed models: Towards meta-analysis of binary outcome with sparse data
( BMC , 2020 , Article)© 2020 The Author(s). Background: In meta-analyses of a binary outcome, double zero events in some studies cause a critical methodology problem. The generalized linear mixed model (GLMM) has been proposed as a valid ... -
Many meta-analyses of rare events in the Cochrane Database of Systematic Reviews were underpowered
( Elsevier , 2021 , Article)Background and ObjectiveMeta-analysis is a statistical method with the ability to increase the power for statistical inference, while it may still face the problem of being underpowered. In this study, we investigated the ... -
Metformin is comparable to insulin for pharmacotherapy in gestational diabetes mellitus: A network meta-analysis evaluating 6046 women.
( Elsevier , 2021 , Article)The comparative efficacy of gestational diabetes (GDM) treatments lack conclusive evidence for choice of first-line treatment. The aim of this study was to compare the efficacy of metformin and glibenclamide to insulin ... -
Methodological assessment of systematic reviews and meta-analyses on COVID-19: A meta-epidemiological study
( Wiley , 2021 , Article)Rationale, aims, and objectives: COVID-19 has caused an ongoing public health crisis. Many systematic reviews and meta-analyses have been performed to synthesize evidence for better understanding this new disease. However, ... -
Methodological quality for systematic reviews of adverse events with surgical interventions: a cross-sectional survey.
( BMC , 2021 , Article)An increasing number of systematic reviews assessed the safety of surgical interventions over time. How well these systematic reviews were designed and conducted determines the reliability of evidence. In this study, we ... -
The odds ratio is “portable” but not the relative risk: Time to do away with the log link in binomial regression
( Elsevier , 2021 , Article)Objectives: In a recent paper we suggest that the relative risk (RR) be replaced with the odds ratio (OR) as the effect measure of choice in clinical epidemiology. In response, Chu, and colleagues raise several points that ... -
Overconfident results with the bivariate random effects model for meta-analysis of diagnostic accuracy studies
( Wiley , 2022 , Article)Meta-analyses of diagnostic accuracy studies are a fundamental component of evidence-based medicine, and they are extensively used in medical imaging and the clinical laboratory. Techniques specifically developed to combine ... -
P-value driven methods were underpowered to detect publication bias: analysis of Cochrane review meta-analyses
( Elsevier , 2019 , Article)To investigate the effect of number of studies in a meta-analysis on the detection of publication bias using p-value driven methods. The proportion of meta-analyses detected by Egger's, Harbord's, Peters', and Begg's tests ... -
PPLS: a privacy-preserving location-sharing scheme in mobile online social networks
( Science in China Press , 2020 , Article)The recent proliferation of mobile devices has given rise to mobile online social networks (mOSNs), an emerging network paradigm that uses social networks as its main design element. As one of the most critical components ... -
Prevalence and determinants of symptomatic COVID-19 infection among children and adolescents in Qatar: A cross sectional analysis of 11445 individuals.
( Cambridge University Press , 2021 , Article)There is a paucity of evidence about the prevalence and risk factors for symptomatic infection among children. This study aimed to describe the prevalence of symptomatic COVID-19 and its risk factors in children and ... -
Protocols for meta-analysis of intervention safety seldom specified methods to deal with rare events
( Elsevier , 2020 , Article Review)ObjectivesMeta-analyses of rare events often generate unstable results, and selective reporting of the results may mislead the health care decision. Developing a synthesis plan for rare events in protocol may help to ... -
Quality versus Risk-of-Bias assessment in clinical research
( Elsevier , 2021 , Article)Assessment of internal validity safeguards implemented by researchers has been used to examine the potential reliability of evidence generated within a study. These safeguards protect against systematic error, and such an ... -
Rapid evidence synthesis approach for limits on the search date: how rapid could it be?
( John Wiley and Sons , 2021 , Article)Rapid reviews have been widely employed to support timely decision-making, and limiting the search date is the most popular approach in published rapid reviews. We assessed the accuracy and workload of search date limits ...
