Browsing by Author "Althani A."
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Genetically unmatched human iPSC and ESC exhibit equivalent gene expression and neuronal differentiation potential.
Marei, Hany E; Althani, A; Lashen, S; Cenciarelli, C; Hasan, Anwarul ( Nature Publishing Group , 2017 , Article)The potential uniformity between differentiation and therapeutic potential of human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) remains debatable. We studied the gene expression profiles, ... -
Nanotubes Impregnated Human Olfactory Bulb Neural Stem Cells Promote Neuronal Differentiation in Trimethyltin-induced Neurodegeneration Rat Model
Marei, H.; Elnegiry, A.; Zaghloul, A.; Althani, A.; Afifi, N.; Abd-Elmaksoud, A.; Farag, A.; Lashen, S.; Rezk, S.; Shouman, Z.; Cenciarelli, C.; Hasan, A.... more authors ... less authors ( Wiley , 2017 , Article)Neural stem cells (NSCs) are multipotent self-renewing cells that could be used in cellular-based therapy for a wide variety of neurodegenerative diseases including Alzheimer's diseases (AD), Parkinson's disease (PD), ... -
Potential of Stem Cell-Based Therapy for Ischemic Stroke.
Marei, Hany E; Hasan, A; Rizzi, R; Althani, A; Afifi, N; Cenciarelli, C; Caceci, Thomas; Shuaib, Ashfaq... more authors ... less authors ( Frontiers Media , 2018 , Article Review)Ischemic stroke is one of the major health problems worldwide. The only FDA approved anti-thrombotic drug for acute ischemic stroke is the tissue plasminogen activator. Several studies have been devoted to assessing the ... -
Qatar Biobank and Qatar Genome Programs Road Map
Althani, A ( OMICS International , 2015 , Article)Qatar Biobank “QBB” is a large-scale, long term medical research initiative for the population of Qatar, which will serve as a platform and driver of biomedical research to achieve benefits for Qatar’s communities. Following ... -
Therapeutic potential of human olfactory bulb neural stem cells for spinal cord injury in rats.
Marei, H.E.; Althani, A.; Rezk, S.; Farag, A.; Lashen, S.; Afifi, N.; Abd-Elmaksoud, A.; Pallini, R.; Casalbore, P.; Cenciarelli, C.; Caceci, T.... more authors ... less authors ( Nature Publishing Group , 2016 , Article)STUDY DESIGN: Adult human olfactory bulb neural stem cells (OBNSCs) were isolated from human patients undergoing craniotomy for tumor resection. They were genetically engineered to overexpresses green fluorescent protein ...