Browsing by Subject "c-Myc"

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Gene Expression Profiling and Protein Analysis Reveal Suppression of the C-Myc Oncogene and Inhibition JAK/STAT and PI3K/AKT/mTOR Signaling by Thymoquinone in Acute Myeloid Leukemia Cells

Almajali, Belal; Johan, Muhammad Farid; Al-Wajeeh, Abdullah Saleh; Wan Taib, Wan Rohani; Ismail, Imilia; Alhawamdeh, Maysa; Al-Tawarah, Nafe M.; Ibrahim, Wisam Nabeel; Al-Rawashde, Futoon Abedrabbu; Al-Jamal, Hamid Ali Nagi... more authors ... less authors ( MDPI , 2022 , Article)
Overexpression of c-Myc plays an essential role in leukemogenesis and drug resistance, making c-Myc an attractive target for cancer therapy. However, targeting c-Myc directly is impossible, and c-Myc upstream regulator ...