Browsing by Publisher "Bentham Science Publishers B.V."
Now showing items 1-11 of 11
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AMP-activated protein kinase as a drug target in chronic kidney disease
( Bentham Science Publishers B.V. , 2018 , Article Review)Background: Chronic kidney disease (CKD) is a condition increasingly affecting millions of individuals worldwide and is ranked as the ninth leading cause of death in the United States. AMP-activated protein kinase (AMPK) ... -
Food insecurity among children in Northern Jordan: Prevalence, socio-economic determinants, and impact on school performance
( Bentham Science Publishers B.V. , 2015 , Article)Background: Food insecurity has been associated with diverse health consequences for children in developed and developing countries, and the interest on food insecurity prevalence and consequences on children have been ... -
Garlic for cardiovascular disease: Prevention or treatment?
( Bentham Science Publishers B.V. , 2017 , Article Review)Cardiovascular disease (CVD) is the leading cause of global mortality with a substantial economic impact. The annual deaths are expected to increase in the next decade. An array of dietary supplements is being used by ... -
IBX/KI promoted synthesis of 2, 5-disubstituted 1, 3, 4-oxadiazoles
( Bentham Science Publishers B.V. , 2018 , Article)Background: Oxadiazoles are privileged scaffolds in different areas of medicinal, pesticidal, polymer and material science. They act as anticancer, benzodiazepine receptor agonists, antimicrobial, analgesic, diuretic and ... -
Liposomes for pulmonary drug delivery: The role of formulation and inhalation device design
( Bentham Science Publishers B.V. , 2017 , Article Review)Liposomes are established drug carriers for inhalation owing to their safety and ability to provide controlled drug release in the lung. These carriers can entrap a wide range of therapeutic molecules for delivery in large ... -
Monoamine oxidase inhibitors extracted from tobacco smoke as neuroprotective factors for potential treatment of Parkinson’s disease
( Bentham Science Publishers B.V. , 2015 , Article)Parkinson’s disease (PD) is a neurodegenerative disease characterized by the loss of mainly the nigrostriatal dopaminergic neurons, which leads to motor dysfunction. Although, most of the drugs are currently used for ... -
Mucoadhesive chitosan derivatives as novel drug carriers
( Bentham Science Publishers B.V. , 2015 , Article)Chitosan on its own is a well-established natural polymer and is widely regarded as a biodegradable, biocompatible and nontoxic material for drug delivery applications. Although unmodified chitosan has some mucoadhesive ... -
Recent advances in synthesis of functionalized β-lactams through cyclization of N-propargyl amine/amide derivatives
( Bentham Science Publishers B.V. , 2018 , Article Review)β-lactams have attracted a significant attention due to their potential biological activities and wide variety of synthetic applications. Developing novel and efficient methods for construction of functionalized β-lactams ... -
Studies on chemistry, spectroscopy and antioxidant activities of chromium(III)-hydrazide complexes
( Bentham Science Publishers B.V. , 2015 , Article)Acid hydrazides are vital chemical entities due to their biological activities. Upon complexation with certain metal ions, their biological activities are known to be positively enhanced. The present work describes the ... -
Synthesis, immunomodulation and cytotoxic effects of vanadium (IV) complexes
( Bentham Science Publishers B.V. , 2014 , Article)Vanadium is known to exhibit several bioactivities and shows potential as a pharmaceutical drug. The current studies were conducted with the goal of synthesizing a new generation of oxovanadium(IV) complexes, investigating ... -
Targeting dopaminergic system for treating nicotine dependence
( Bentham Science Publishers B.V. , 2016 , Article)Background: Smoking is the world's leading cause of preventable death among populations. Cigarette smoking increases the risk of numerous health problems, including heart diseases, stroke, atherosclerosis and many types ...