Browsing by Publisher "Verduci Editore srl"

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An in silico analysis of the impact of POLE mutations on cladribine docking

Loganathan, L.; Al-Haidose, A.; Ganesh Kumar, A.; Sujatha, L. B.; Carlus, F. H.; Alharbi, A.; Alhyassat, S.; Muthusamy, K.; Carlus, S. J.; Abdallah, A. M.... more authors ... less authors ( Verduci Editore srl , 2022 , Article)
OBJECTIVE: Polymerase ε exonuclease (POLE) is an enzyme involved in DNA replication and may be an attractive therapeutic target in various cancers. Here we sought to model the impact of specific POLE mutations on protein ...