Copper Complexes Of Di-, Tri-, And Tetra-Peptides Containing Tryptophan, Histidine And Arginine

Abstract

Fifty Seven copper complexes of di-, tri-. and tetra-peptides containing tryptophan, histidine and arginine are studied spectrophotometrically. The ^a, and colour of the complexes are dependent on the sequence of the amino acid in the dipeptide methyl esters of tryptophan and arginine; and independent on the sequence of dipeptides of histidine or in any of the tri- and tetra-peptides of histidine, arginine and tryptophan. The results achieved confirmed that the nitrogen atoms of the indole nucleus in tryptophan, imidazole ring in histidine and guanidino group in arginine do not participate in complex formation of all studied di-, tri- and tetra-peptides. However. the amide group and the hydrazide group of dipeptide amides and dipeptide hydrazides participate in complex formation.