Co-presence of Epstein-Barr virus and high-risk human papillomaviruses in Syrian colorectal cancer samples.
المؤلف | Malki, Mohammed I |
المؤلف | Gupta, Ishita |
المؤلف | Fernandes, Queenie |
المؤلف | Aboulkassim, Tahar |
المؤلف | Yasmeen, Amber |
المؤلف | Vranic, Semir |
المؤلف | Al Moustafa, Ala-Eddin |
المؤلف | Al-Thawadi, Hamda A |
تاريخ الإتاحة | 2020-03-22T09:48:21Z |
تاريخ النشر | 2020-03-18 |
اسم المنشور | Human Vaccines and Immunotherapeutics |
المعرّف | http://dx.doi.org/10.1080/21645515.2020.1726680 |
الاقتباس | Mohammed I. Malki, Ishita Gupta, Queenie Fernandes, Tahar Aboulkassim, Amber Yasmeen, Semir Vranic, Ala-Eddin Al Moustafa & Hamda A. Al-Thawadi (2020) Co-presence of Epstein–Barr virus and high-risk human papillomaviruses in Syrian colorectal cancer samples, Human Vaccines & Immunotherapeutics, DOI: 10.1080/21645515.2020.1726680 |
الرقم المعياري الدولي للكتاب | 2164-5515 |
الملخص | We recently performed two studies exploring the presence of Epstein-Barr virus (EBV) and high-risk human papillomaviruses (HPVs) types 16, 18, 31, 33 and 35 in human colorectal cancers from the Syrian population. Herein, we report that EBV and high-risk HPVs are co-present in colorectal cancers from Syria. We reveal that 17 (~17%) of 102 cancer samples are positive for both EBV and high-risk HPVs and their co-presence is associated with high/intermediate grade invasive carcinomas. These data suggest that EBV and high-risk HPVs are co-present in human colorectal cancers where they might cooperate on the initiation and/or progression of these cancers. Thus, we believe that future studies are necessary to confirm the co-presence of these oncoviruses and their cooperative role in human colorectal carcinogenesis. |
راعي المشروع | This work was supported by grants from Qatar University: QUHI-CMED-19/20-1 and GCC # 2017-002 QU/KU. |
اللغة | en |
الناشر | Taylor & Francis |
الموضوع | EBV Syrian population cancer phenotype colorectal cancer high-risk HPV |
النوع | Article |
ESSN | 2164-554X |
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