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المؤلفDosekova, Erika
المؤلفFilip, Jaroslav
المؤلفBertok, Tomas
المؤلفBoth, Peter
المؤلفKasak, Peter
المؤلفTkac, Jan
تاريخ الإتاحة2020-10-01T11:39:53Z
تاريخ النشر2017
اسم المنشورMedicinal Research Reviews
المصدرScopus
معرّف المصادر الموحدhttp://dx.doi.org/10.1002/med.21420
معرّف المصادر الموحدhttp://hdl.handle.net/10576/16359
الملخصThis review comprehensively covers the most recent achievements (from 2013) in the successful integration of nanomaterials in the field of glycomics. The first part of the paper addresses the beneficial properties of nanomaterials for the construction of biosensors, bioanalytical devices, and protocols for the detection of various analytes, including viruses and whole cells, together with their key characteristics. The second part of the review focuses on the application of nanomaterials integrated with glycans for various biomedical applications, that is, vaccines against viral and bacterial infections and cancer cells, as therapeutic agents, for in vivo imaging and nuclear magnetic resonance imaging, and for selective drug delivery. The final part of the review describes various ways in which glycan enrichment can be effectively done using nanomaterials, molecularly imprinted polymers with polymer thickness controlled at the nanoscale, with a subsequent analysis of glycans by mass spectrometry. A short section describing an active glycoprofiling by microengines (microrockets) is covered as well.
راعي المشروعThis publication was made possible by NPRP grant number 6-381-1-078 from the Qatar National Research Fund (a member of the Qatar Foundation)
اللغةen
الناشرJohn Wiley and Sons Inc.
الموضوعcell tissue targeting/imaging and drug delivery
glycan enrichment and active glycoprofiling
glycan sensing
glycan-based vaccines/therapeutics
glycomics
nanomaterials
nanotechnology
العنوانNanotechnology in Glycomics: Applications in Diagnostics, Therapy, Imaging, and Separation Processes
النوعArticle Review
الصفحات514-626
رقم العدد3
رقم المجلد37
dc.accessType Abstract Only


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