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AuthorPolakovic, Milan
AuthorSvitel, Juraj
AuthorBucko, Marek
AuthorFilip, Jaroslav
AuthorNedela, Vilem
AuthorAnsorge-Schumacher, Marion B.
AuthorGemeiner, Peter
Available date2020-10-12T09:21:46Z
Publication Date2017
Publication NameBiotechnology Letters
ResourceScopus
URIhttp://dx.doi.org/10.1007/s10529-017-2300-y
URIhttp://hdl.handle.net/10576/16386
AbstractViable microbial cells are important biocatalysts in the production of fine chemicals and biofuels, in environmental applications and also in emerging applications such as biosensors or medicine. Their increasing significance is driven mainly by the intensive development of high performance recombinant strains supplying multienzyme cascade reaction pathways, and by advances in preservation of the native state and stability of whole-cell biocatalysts throughout their application. In many cases, the stability and performance of whole-cell biocatalysts can be highly improved by controlled immobilization techniques. This review summarizes the current progress in the development of immobilized whole-cell biocatalysts, the immobilization methods as well as in the bioreaction engineering aspects and economical aspects of their biocatalytic applications.
Languageen
PublisherSpringer Netherlands
SubjectBiocatalysis
Immobilization methods
Immobilized whole-cell biocatalyst
Multienzyme cascade reactions
Process economics
Reaction engineering
TitleProgress in biocatalysis with immobilized viable whole cells: systems development, reaction engineering and applications
TypeArticle Review
Pagination667-683
Issue Number5
Volume Number39
dc.accessType Abstract Only


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