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المؤلفMathew, Shilu
المؤلفFaheem, Muhammed
المؤلفHassain, Neeraja A
المؤلفBenslimane, Fatiha M
المؤلفThani, Asmaa A Al
المؤلفZaraket, Hassan
المؤلفYassine, Hadi M
تاريخ الإتاحة2021-01-13T06:03:41Z
تاريخ النشر2020-12-01
اسم المنشورVaccines
المعرّفhttp://dx.doi.org/10.3390/vaccines9010011
الاقتباسMathew, S.; Faheem, M.; Hassain, N.A.; Benslimane, F.M.; Al Thani, A.A.; Zaraket, H.; Yassine, H.M. Platforms Exploited for SARS-CoV-2 Vaccine Development. Vaccines 2021, 9, 11.
معرّف المصادر الموحدhttp://hdl.handle.net/10576/17300
الملخصThe novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the only zoonotic-origin coronavirus (CoV) that has reached the pandemic stage. The virus uses its spike (S) glycoprotein to attach to the host cells and initiate a cascade of events that leads to infection. It has sternly affected public health, economy, education, and social behavior around the world. Several scientific and medical communities have mounted concerted efforts to limit this pandemic and the subsequent wave of viral spread by developing preventative and potential vaccines. So far, no medicine or vaccine has been approved to prevent or treat coronavirus disease 2019 (COVID-19). This review describes the latest advances in the development of SARS-CoV-2 vaccines for humans, mainly focusing on the lead candidates in clinical trials. Moreover, we seek to provide both the advantages and the disadvantages of the leading platforms used in current vaccine development, based on past vaccine delivery efforts for non-SARS CoV-2 infections. We also highlight the population groups who should receive a vaccine against COVID-19 in a timely manner to eradicate the pandemic rapidly.
اللغةen
الناشرMDPI
الموضوعCovid-19
SARS-CoV-2
clinical trials
vaccine platforms
vaccines
العنوانPlatforms Exploited for SARS-CoV-2 Vaccine Development.
النوعArticle Review
رقم العدد1
رقم المجلد9
ESSN2076-393X
dc.accessType Open Access


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