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المؤلفAl-Hadidi, Sara H.
المؤلفAlhussain, Hashim
المؤلفAbdel Hadi, Hamad
المؤلفJohar, Alreem
المؤلفYassine, Hadi M.
المؤلفAl Thani, Asmaa A.
المؤلفEltai, Nahla O.
تاريخ الإتاحة2021-06-08T06:55:46Z
تاريخ النشر2021-06-01
اسم المنشورMicrobial Drug Resistance
المعرّفhttp://dx.doi.org/10.1089/mdr.2020.0619
الاقتباسSara H. Al-Hadidi, Hashim Alhussain, Hamad Abdel Hadi, Alreem Johar, Hadi M. Yassine, Asmaa A. Al Thani, and Nahla O. Eltai.Microbial Drug Resistance.ahead of printhttp://doi.org/10.1089/mdr.2020.0619
الرقم المعياري الدولي للكتاب1076-6294
معرّف المصادر الموحدhttp://hdl.handle.net/10576/20549
الملخصObjectives: Over the last decades, there has been a significant increase in antimicrobial prescribing and consumption associated with the development of patients’ adverse events and antimicrobial resistance (AMR) to the point of becoming a global priority. This study aims at evaluating antibiotic prescribing during COVID- 19 pandemic from November 2019 to December 2020. Materials and Methods: A systematic review was conducted primarily through the NCBI database, using PRISMA guidelines to identify relevant literature for the period between November 1, 2019 and December 19, 2020, using the keywords: COVID-19 OR SARS-Cov-2 AND antibiotics restricted to the English language excluding nonclinical articles. Five hundred twenty-seven titles were identified; all articles fulfilling the study criteria were included, 133 through the NCBI, and 8 through Google Scholar with a combined total of 141 studies. The patient’s spectrum included all ages from neonates to elderly with all associated comorbidities, including immune suppression. Results: Of 28,093 patients included in the combined studies, 58.7% received antibiotics (16,490/28,093), ranging from 1.3% to 100% coverage. Antibiotics coverage was less in children (57%) than in adults with comorbidities (75%). Broad-spectrum antibiotics were prescribed presumptively without pathogen identifications, which might contribute to adverse outcomes. Conclusions: During the COVID-19 pandemic, there has been a significant and wide range of antibiotic prescribing in patients affected by the disease, particularly in adults with underlying comorbidities, despite the paucity of evidence of associated bacterial infections. The current practice might increase patients’ immediate and long-term risks of adverse events, susceptibility to secondary infections as well as aggravating AMR
اللغةen
الناشرMary Ann Liebert
الموضوعCOVID-19
antibiotics
antimicrobial stewardship
resistance
AMR
العنوانThe Spectrum of Antibiotic Prescribing During COVID-19 Pandemic: A Systematic Literature Review
النوعArticle Review
ESSN1931-8448
dc.accessType Open Access


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