Academic: Recent submissions
Now showing items 1-20 of 28739
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Metabolomics analyses reveal the crucial role of ERK in regulating metabolic pathways associated with the proliferation of human cutaneous T-cell lymphoma cells treated with Glabridin
( John Wiley and Sons , 2024 , Article)Cutaneous T-cell lymphomas (CTC) are a heterogeneous group of T-cell lymphoproliferative malignancies of the skin with limited treatment options, increased resistance and remission. Metabolic reprogramming is vital in ... -
Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
( Elsevier Ltd. , 2024 , Article)Background: Understanding the health consequences associated with exposure to risk factors is necessary to inform public health policy and practice. To systematically quantify the contributions of risk factor exposures to ... -
Correlates of childhood caries: A study in Qatar
( John Wiley and Sons , 2023 , Article)Background: The prevalance of dental caries in children in Qatar is high, which necessitates preventive efforts. Aim: To identify the sociodemographic and behavioural correlates of dental caries in the primary dentition ... -
Successful treatment of pachyonychia congenita with simvastatin
( John Wiley and Sons , 2023 , Other)Pachyonychia congenita (PC) is a rare autosomal-dominant genodermatosis. It is an ectodermal, dysplastic disorder of keratinization that typically arises at birth or early infancy due to keratin-specific gene mutations, ... -
Atopic dermatitis: A global health perspective
( John Wiley and Sons , 2023 , Article)The International Society of AD (ISAD) organized a roundtable on global aspects of AD at the WCD 2023 in Singapore. According to the Global Burden of Disease (GBD) consortium, at least 171 million individuals were affected ... -
Severe atopic dermatitis in an Asian-Arabic population treated with dupilumab: A retrospective observational study
( John Wiley and Sons , 2024 , Other)Atopic dermatitis (AD) is a common, inflammatory skin disease characterized by a TH2-deviated immune response in the acute phase and a TH2/TH1/TH17/TH22-skewed immune response in the chronic phase1 associated with pruritus. ... -
Retrospective evaluation of a TEN/SJS series managed with a new treatment protocol
( John Wiley and Sons , 2024 , Other)Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare, life-threatening diseases without standardized treatment. The mortality rate ranges from 20% to 50%, and can reach up to 90%, based on the ... -
Cytochrome P450 Enzymes: The Old Pandora's Box with an Ever-Growing Hope for Therapy Optimization and Drug Development-Editorial
( American Society for Pharmacology and Experimental Therapy (ASPET) , 2024 , Other)In 1841, the notion of drug metabolism in the body was coined with the discovery of hippuric acid as a metabolite of benzoic acid in urine of human subjects (Ure, 1841). Since then, there has been an explosive growth in ... -
Effectiveness of 2D magnesium phosphate hydrogel for surgical decontamination of dental implants: A case series
( John Wiley and Sons , 2024 , Article)Dental implants, recognized for their enhanced functionality and aesthetic outcomes, are susceptible to peri-implant mucositis and subsequent peri-implantitis when oral hygiene is inadequate. Effective biofilm management ... -
Exploring the Impact of Cigarette Smoke Extracts on Vitamin B12: Insights into the Transformation of Methylcobalamin and Hydroxycobalamin to Cyanocobalamin through in Vitro Evaluation
( John Wiley and Sons , 2024 , Article)Vitamin B12 (cobalamin) is a water-soluble molecule required for the proper functioning of metabolism, blood and DNA synthesis, and neurological development. Vitamin B12 exists in several forms: methylcobalamin (MeCbl), ... -
The Rehabilitation Landscape in a Low-to-Middle-Income Country: Stakeholder Perspectives and Policy Implications—A Qualitative Study
( SAGE , 2024 , Article)The need for rehabilitation is increasing on a global level due to a rise in non-communicable diseases, aging and medical advances, and in South Africa (SA), due to the quadruple burden of disease. More information is ... -
Comparing E-Cigarettes and Traditional Cigarettes in Relation to Myocardial Infarction, Arrhythmias, and Sudden Cardiac Death: A Systematic Review and Meta-Analysis
( SAGE , 2025 , Article)Background: The use of electronic cigarettes (e-cigarettes) as a perceived safer alternative to traditional cigarettes has grown rapidly. However, the cardiovascular risks associated with e-cigarettes compared to regular ... -
Enhancing medication management of older adults in Qatar: healthcare professionals’ perspectives on challenges, barriers and enabling solutions
( SAGE , 2024 , Article)Background: Polypharmacy and potentially inappropriate medications are significant challenges in older adults’ medication management. The Consolidated Framework for Implementation Research (CFIR) is a comprehensive approach ... -
When and Why Do Investors Prefer Copycats?
( Berkeley Haas , 2024 , Article)Investors, particularly venture capitalists, often face the challenging decision of where to allocate their resources. Among the various options, they might encounter original ideas, innovative startups, and companies that ... -
Unveiling the Dialectics of Cloud-ERP Technology: A Multi-Case Study on the Logic Multiplicity and Emergent Interactions among IT and Finance Professionals
( Elsevier , 2023 , Article)This study examines a relatively neglected account of how Cloud ERP-induced dialectics are inherited by multiple logics and managed by professionals in IT and finance. Using logic multiplicity, this investigation was ... -
Unveiling hidden patterns between managerial assumptions, international market orientation, and performance: an unexplored journey into Japanese SMEs
( Emerald Publishing , 2024 , Article)Purpose This study seeks to investigate how managerial assumptions shape international market orientation (IMO) and how IMO, in turn, affects the performance of small and medium-sized enterprises (SMEs), drawing from ... -
Uncovering the International view of e-government studies: a bibliometric review
( Inderscience Publishers , 2024 , Article)This paper aims to undertake a bibliometric analysis of e-government studies utilising the Scopus database. The study followed an archival review approach with data collected from the Scopus database. A mixed method was ... -
The Impact of Cultural Dimensions and Quality of Life on Smartphone Addiction and Employee Performance: The Moderating Role of Quality of Life
( Springer Nature , 2024 , Article)Smartphones, while ubiquitous and beneficial, can lead to problematic use. This study investigates the intricate interplay between cultural dimensions, smartphone addiction, and employee performance. Through the lens of ... -
When does entrepreneurial leadership enhance supply chain resilience? A three-way interaction analysis
( Emerald Publishing , 2024 , Article)Purpose: The research on entrepreneurial leadership (EL) and supply chain resilience (SCR) relationship is still in its exploration stage. Previous research indicates that EL is important for enhancing supply chain ... -
What drives cryptocurrency pump and dump schemes: Coin versus market factors?
( Elsevier , 2024 , Article)This paper investigates both coin-specific and market-based factors that drive cryptocurrency pump-and-dump schemes. It analyzes a data set comprising 1457 pump events that occurred from January 3, 2018, to January 2, 2022. ...