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AuthorKlukova, L.
AuthorFilip, J.
AuthorBelicky, S.
AuthorVikartovska, A.
AuthorTkac, J.
Available date2021-09-01T10:02:43Z
Publication Date2016
Publication NameAnalyst
ResourceScopus
URIhttp://dx.doi.org/10.1039/c6an00793g
URIhttp://hdl.handle.net/10576/22366
AbstractA label-free ultrasensitive impedimetric biosensor with lectin immobilised on graphene oxide (GO) for the detection of glycoproteins from 1 aM is shown here. This is the first time a functional lectin biosensor with lectin directly immobilised on a graphene-based interface without any polymer modifier has been described. The study also shows that hydrophilic oxidative debris present on GO has a beneficial effect on the sensitivity of (8.46 - 0.20)% per decade for the lectin biosensor compared to the sensitivity of (4.52 - 0.23)% per decade for the lectin biosensor built up from GO with the oxidative debris washed out.
Languageen
PublisherRoyal Society of Chemistry
Subjectglycoprotein
graphite
lectin
oxide
chemistry
electrochemical analysis
genetic procedures
Biosensing Techniques
Electrochemical Techniques
Glycoproteins
Graphite
Lectins
Oxides
TitleGraphene oxide-based electrochemical label-free detection of glycoproteins down to aM level using a lectin biosensor
TypeArticle
Pagination4278-4282
Issue Number14
Volume Number141
dc.accessType Abstract Only


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