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AuthorMrlík, Miroslav
AuthorIlčíková, Markéta
AuthorCvek, Martin
AuthorPavlínek, Vladimír
AuthorZahoranová, Anna
AuthorKroneková, Zuzana
AuthorKasak, Peter
Available date2021-09-07T06:16:23Z
Publication Date2016
Publication NameRSC Advances
ResourceScopus
ISSN20462069
URIhttp://dx.doi.org/10.1039/c6ra03919g
URIhttp://hdl.handle.net/10576/22841
AbstractIn this study, surface modification of carbonyl iron (CI) particles with sulfobetaine moieties (SBE) was performed by the silanization of activated CI to form stable CI-SBE particles. The modification led to a significant improvement of the thermo-oxidation stability and a negligible suppression of the magnetization of the particles, as revealed by thermogravimetric analysis and vibrating sample magnetometry, respectively. The effect of a magnetic field and temperature on the magnetorheological performance of particle suspensions was investigated using a rotational rheometer in order to clarify the suitability of these systems for the local embolization of blood veins. The suspension based on CI-SBE exhibited a pseudoplastic behaviour and a tunable yield stress in a range from 0.3-4 kPa at the normal human body temperature. Moreover, cell viability for fibroblasts and macrophages was examined via MTT assay, which revealed their suitability for the intended applications for the local embolization of blood veins. The Royal Society of Chemistry 2016.
Languageen
PublisherRoyal Society of Chemistry
SubjectBiocompatibility
Biomagnetism
Blood
Cell culture
Metal coatings
Silicones
Surface treatment
Suspensions (fluids)
Thermogravimetric analysis
Thermooxidation
Yield stress
Bio-compatible systems
Cell viability
Human body temperature
Magneto-rheological
Particle suspensions
Rotational rheometer
Silicone-oil suspensions
Vibrating sample magnetometry
Suspensions (components)
TitleCarbonyl iron coated with a sulfobetaine moiety as a biocompatible system and the magnetorheological performance of its silicone oil suspensions
TypeArticle
Pagination32823-32830
Issue Number39
Volume Number6
dc.accessType Abstract Only


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